Bacterial Infection

Regulatory effects of mangiferin on LPS-induced inflammatory responses and intestinal flora imbalance during sepsis.

Studies suggest that mangiferin (MAF) has good therapeutic effects on chronic bronchitis and hepatitis. Also, it is one of the antiviral ingredients in Bunge. However, its effect on the LPS-induced inflammation and intestinal flora during sepsis remains unclear yet. In the present study, LPS-stimulated inflammation RAW264.7 cells and LPS-induced sepsis mice were used to evaluate the efficacy of M...

Antibiotic resistance gene-free probiont administration to tilapia for growth performance and resistance.

BACKGROUND AND AIM: The rapid development of aquaculture as a major food sector is accompanied by challenges, including diseases that affect tilapia farming worldwide. One such infectious disease caused by poses a serious threat to tilapia populations. Probiotics have emerged as a potentially safe preventive measure against infection. However, antimicrobial resistance from antibiotic-resistant b...

Use of Organic Acids to Control and Infection in Swine Jowl Fat.

The objective of this work was to evaluate the mortality of and inoculated in fresh swine jowls treated with different concentrations of organic aci...

Improved antimicrobial activities of essential oils nanoencapsulated into hydroxypropyl-beta-cyclodextrins.

Natural antimicrobials have recently gained increasing interest over synthetic antimicrobials to overcome foodborne pathogens and food microbial conta...

Evaluating Antioxidant Performance, Biosafety, and Antimicrobial Efficacy of Extract and Microwave-Assisted Synthesis of Biogenic Silver Nano-Antibiotics.

From the traditional Chinese medicine point of view, although extract (HCE) possesses an incredible amount of phytonutrients and exhibits antioxidant...

Leveraging machine learning to distinguish between bacterial and viral induced pharyngitis using hematological markers: a retrospective cohort study.

Accurate differentiation between bacterial and viral-induced pharyngitis is recognized as essential for personalized treatment and judicious antibioti...

Investigating Novel IspE Inhibitors of the MEP Pathway in Mycobacterium.

In a recent effort to mitigate harm from human pathogens, many biosynthetic pathways have been extensively evaluated for their ability to inhibit path...

Advances in machine learning-based bacteria analysis for forensic identification: identity, ethnicity, and site of occurrence.

When faced with an unidentified body, identifying the victim can be challenging, particularly if physical characteristics are obscured or masked. In r...

Determination of ertapenem in plasma and ascitic fluid by UHPLC-MS/MS in cirrhotic patients with spontaneous bacterial peritonitis.

OBJECTIVES: Spontaneous bacterial peritonitis is a frequent severe complication in cirrhotic patients with ascites. Carbapenem antibiotics are current...

Discovery of a structural class of antibiotics with explainable deep learning.

The discovery of novel structural classes of antibiotics is urgently needed to address the ongoing antibiotic resistance crisis. Deep learning approac...

High-Yield Preparation of American Oyster Defensin (AOD) via a Small and Acidic Fusion Tag and Its Functional Characterization.

The marine peptide, American oyster defensin (AOD), is derived from and exhibits a potent bactericidal effect. However, recombinant preparation has n...

Antibacterial, Resistance Modulation, Anti-Biofilm Formation, and Efflux Pump Inhibition Properties of (Willd.) N. Halle (Celastraceae) Stem Extract and Its Constituents.

This study investigated the antibacterial, resistance modulation, biofilm inhibition, and efflux pump inhibition potentials of stem extract and its c...

Evaluation of Anti-Bacterial and Anti-Biofilm Activity of Native Probiotic Strains of Lactobacillus Extracts.

BACKGROUND: Lactic acid bacteria produce various beneficial metabolites, including antimicrobial agents. Owing to the fast-rising antibiotic resistanc...

Curcumin Aattenuates the Expression of Metalloprotease (AHA_0978) and Serine Protease (AHA_3857) Genes in Aeromonas Hydrophila.

BACKGROUND: Aeromonas hydrophila is a pathogenic bacterium responsible for various infections in humans and animals. Bacterial exoproteases are consid...

Exopolysaccharides from and : Bioactivities, gut microbiome effects, and fermented milk rheology.

Exopolysaccharides (EPSs) are carbohydrate polymers that can be produced from probiotic bacteria. This study characterized the EPSs from (EPS-LB13) a...

Perspective: Limiting Antimicrobial Resistance with Artificial Intelligence/Machine Learning.

The author traces his experience with the application of computers in clinical microbiology over the past 60 years, specifically in directing clinicia...

From the diagnosis of infectious keratitis to discriminating fungal subtypes; a deep learning-based study.

Infectious keratitis (IK) is a major cause of corneal opacity. IK can be caused by a variety of microorganisms. Typically, fungal ulcers carry the wor...

Machine learning identification of Pseudomonas aeruginosa strains from colony image data.

When grown on agar surfaces, microbes can produce distinct multicellular spatial structures called colonies, which contain characteristic sizes, shape...

Argan: Phytochemical profiling and evaluation of the antioxidant, hypoglycemic, and antibacterial properties of its fruit pulp extracts.

Herein, we isolated three triterpenoid saponins from the methanol extract of the fruit pulp of argan The structures of the identified compounds were d...

Structure, dynamics, and stability of the smallest and most complex 7 protein knot.

Proteins can spontaneously tie a variety of intricate topological knots through twisting and threading of the polypeptide chains. Recently developed a...