Chemotherapy

Evaluation of Cytotoxic Activity Alkaloid Fractions of DC. Fruits.

AIM: This study was carried out to investigate cytotoxic activity towards T47D, 4T1, MCF-7, HeLa, an...

ASO Author Reflections: Use of Machine Learning to Identify Patients with Intrahepatic Cholangiocarcinoma Who Could Benefit More from Neoadjuvant Therapies.

Multifunctional Nanorobot System for Active Therapeutic Delivery and Synergistic Chemo-photothermal Therapy.

Nanorobots are safe and exhibit powerful functionalities, including delivery, therapy, and diagnosis...

Novel approaches for glioblastoma treatment: Focus on tumor heterogeneity, treatment resistance, and computational tools.

BACKGROUND: Glioblastoma (GBM) is a highly aggressive primary brain tumor. Currently, the suggested ...

Natural language processing of electronic health records is superior to billing codes to identify symptom burden in hemodialysis patients.

Symptoms are common in patients on maintenance hemodialysis but identification is challenging. New i...

Toward Automated Bladder Tumor Stratification Using Confocal Laser Endomicroscopy.

Urothelial carcinoma of the bladder (UCB) is the most common urinary cancer. White-light cystoscopy...

Label-Free Estimation of Therapeutic Efficacy on 3D Cancer Spheres Using Convolutional Neural Network Image Analysis.

Despite recent advances in cancer treatment, developing better therapeutic reagents remains an essen...

Deep Learning Based on Standard H&E Images of Primary Melanoma Tumors Identifies Patients at Risk for Visceral Recurrence and Death.

PURPOSE: Biomarkers for disease-specific survival (DSS) in early-stage melanoma are needed to select...

A Machine Learning-Based Prediction Platform for P-Glycoprotein Modulators and Its Validation by Molecular Docking.

P-glycoprotein (P-gp) is an important determinant of multidrug resistance (MDR) because its overexpr...

Machine learning prediction of emesis and gastrointestinal state in ferrets.

Although electrogastrography (EGG) could be a critical tool in the diagnosis of patients with gastro...

cytogenotoxic evaluation of sertraline.

Sertraline (SRT) is an antidepressant agent used as a neuronal selective serotonin-reuptake inhibito...

Antioxidant, Anti-Melanogenic and Anti-Wrinkle Effects of .

In this study, the antioxidant, anti-xanthine oxidase, anti-melanogenic and anti-wrinkle effects of ...

[Prediction of chemotherapy response in primary osteosarcoma using the machine learning technique on radiomic data].

INTRODUCTION: Osteosarcoma is the most common malignant bone tumor before 25 years of age. Response ...

A machine learning algorithm predicts molecular subtypes in pancreatic ductal adenocarcinoma with differential response to gemcitabine-based versus FOLFIRINOX chemotherapy.

PURPOSE: Development of a supervised machine-learning model capable of predicting clinically relevan...

Towards early monitoring of chemotherapy-induced drug resistance based on single cell metabolomics: Combining single-probe mass spectrometry with machine learning.

Despite the presence of methods evaluating drug resistance during chemotherapies, techniques, which ...

Machine-Learning Prediction of Tumor Antigen Immunogenicity in the Selection of Therapeutic Epitopes.

Current tumor neoantigen calling algorithms primarily rely on epitope/major histocompatibility compl...

Designing combination therapies with modeling chaperoned machine learning.

Chemotherapy resistance is a major challenge to the effective treatment of cancer. Thus, a systemati...

Growth Inhibitory and Pro-Apoptotic Effects of Ornamental Pomegranate Extracts in Du145 Human Prostate Cancer Cells.

Prostate cancer is the most common form of cancer in the male. Epidemiological studies have associa...

Improvement of Epitope Prediction Using Peptide Sequence Descriptors and Machine Learning.

In this work, we improved a previous model used for the prediction of proteomes as new B-cell epitop...

Cloisite Microrobots as Self-Propelling Cleaners for Fast and Efficient Removal of Improvised Organophosphate Nerve Agents.

Naturally available microclays are well-known materials with great adsorption capabilities that are ...

Precision Surgical Therapy for Adenocarcinoma of the Esophagus and Esophagogastric Junction.

INTRODUCTION: To facilitate the initial clinical decision regarding whether to use esophagectomy alo...