Chemotherapy

Lycopene-rich extract from red guava (Psidium guajava L.) displays cytotoxic effect against human breast adenocarcinoma cell line MCF-7 via an apoptotic-like pathway.

This study investigated a lycopene-rich extract from red guava (LEG) for its chemical composition us...

Synthesis of poly(1,2-glycerol carbonate)-paclitaxel conjugates and their utility as a single high-dose replacement for multi-dose treatment regimens in peritoneal cancer.

Current chemotherapeutic dosing strategies are limited by the toxicity of anticancer agents and ther...

Extended Adjuvant Aromatase Inhibitor Therapy in Post-Menopausal Women.

PURPOSE OF THE REVIEW: To understand the evidence for extending adjuvant aromatase inhibitor (AI) th...

Validation of a Machine Learning Approach for Venous Thromboembolism Risk Prediction in Oncology.

Using kernel machine learning (ML) and random optimization (RO) techniques, we recently developed a ...

Mesoporous carbon nanomaterials induced pulmonary surfactant inhibition, cytotoxicity, inflammation and lung fibrosis.

Environmental exposure and health risk upon engineered nanomaterials are increasingly concerned. The...

Exploration of Wedelia chinensis leaf-assisted silver nanoparticles for antioxidant, antibacterial and in vitro cytotoxic applications.

Green synthetic route of silver nanoparticles (AgNPs) has already been proved to be an advantageous ...

Strategy of metal iron doping and green-mediated ZnO nanoparticles: dissolubility, antibacterial and cytotoxic traits.

Undoped and Fe-doped ZnO nanoparticles (NPs) were synthesized using leaf extract as a reducing agen...

Comparing the Effect of Adding Fentanyl, Sufentanil, and Placebo with Intrathecal Bupivacaine on Duration of Analgesia and Complications of Spinal Anesthesia in Patients Undergoing Cesarean Section.

BACKGROUND: Spinal anesthesia is the method of choice for most elective and emergency Cesarean secti...

Bladder Cancer Treatment Response Assessment in CT using Radiomics with Deep-Learning.

Cross-sectional X-ray imaging has become the standard for staging most solid organ malignancies. How...

Reinforcement learning-based control of drug dosing for cancer chemotherapy treatment.

The increasing threat of cancer to human life and the improvement in survival rate of this disease d...

Tramadol sparing effect of dexmedetomidine as an adjuvant with lignocaine in preoperative stellate ganglion block for postoperative pain relief following upper limb surgeries.

BACKGROUND: Recent literature has established the role of stellate ganglion block (SGB) for manageme...

Effects of Oleo Gum Resin of L. on Senescence in Human Dermal Fibroblasts: - Asafoetida reverses senescence in fibroblasts.

OBJECTIVES: Based on data from Chinese and Indian traditional herbal medicines, gum resin of (somet...

Biological activities of plant extracts from and : An antimalarial, antitrypanosomal and cytotoxity evaluation.

The cytotoxic, antiplasmodial, and antitrypanosomal activities of two medicinal plants traditionally...

Synthesis and Biological Evaluations of Ring Substituted Tetrahydroisoquinolines (THIQs) as Anti-Breast Cancer Agents.

Breast cancer is a leading cause of mortality among women, resulting in more than half a million dea...

A Novel Case of Somatic Mutation in Pediatric-Onset Aldosterone-Producing Adenoma.

Aldosterone-producing adenoma (APA), a subtype of primary aldosteronism, is a common cause of second...

PAK6-Associated Support Vector Machine Classifier: A New Way to Evaluate Response and Survival of Gastric Cancer Treated by 5-FU/Oxaliplatin Chemotherapy.

Mesenteric approach during pancreaticoduodenectomy for pancreatic ductal adenocarcinoma.

Mesenteric approach is an artery-first approach during pancreaticoduodenectomy (PD). In the present ...

A Comparison of Aromatherapy to Standard Care for Relief of PONV and PDNV in Ambulatory Surgical Patients.

PURPOSE: To determine effectiveness of aromatherapy (AT) compared with standard care (SC) for postop...

Stability of sodium bicarbonate injection 8.4% in syringes over a six-week period in refrigerated temperature.

Background Dysfunctional central venous catheter prohibits the administration of potential life-savi...

A deep learning based strategy for identifying and associating mitotic activity with gene expression derived risk categories in estrogen receptor positive breast cancers.

The treatment and management of early stage estrogen receptor positive (ER+) breast cancer is hinder...

Predicting DPP-IV inhibitors with machine learning approaches.

Dipeptidyl peptidase IV (DPP-IV) is a promising Type 2 diabetes mellitus (T2DM) drug target. DPP-IV ...