Clinical Trials

Function of a multimodal signal: A multiple hypothesis test using a robot frog.

Multimodal communication may evolve because different signals may convey information about the signaller (content-based selection), increase efficacy of signal processing or transmission through the environment (efficacy-based selection), or modify the production of a signal or the receiver's response to it (inter-signal interaction selection). To understand the function of a multimodal signal (ag...

Caffeine-carbohydrate mouth-rinsing counter-acts an observed negative effect of mouth-rinsing procedure during sprint-endurance training performance in fasted athletes: A pilot study.

Carbohydrate mouth-rinsing has been reported to benefit endurance performance in athletes intermittently fasting; however, in the fasted state, the effects of combined caffeine and carbohydrate (CAF-CHO) mouth-rinsing on sprint-endurance performance are unknown. We determined the effects of CAF-CHO mouth-rinsing on kinetics, kinematics, and perceptual measures during a sprint-endurance performance...

Combining genetic risk score with artificial neural network to predict the efficacy of folic acid therapy to hyperhomocysteinemia.

Artificial neural network (ANN) is the main tool to dig data and was inspired by the human brain and nervous system. Several studies clarified its app...

Developing an Analytical Pipeline to Classify Patient Safety Event Reports Using Optimized Predictive Algorithms.

BACKGROUND: Patient safety event reports provide valuable insight into systemic safety issues but deriving insights from these reports requires comput...

Differential power of placebo across major psychiatric disorders: a preliminary meta-analysis and machine learning study.

The placebo effect across psychiatric disorders is still not well understood. In the present study, we conducted meta-analyses including meta-regressi...

A Smart Capacitive Sensor Skin with Embedded Data Quality Indication for Enhanced Safety in Human-Robot Interaction.

Smart sensors are an integral part of the Fourth Industrial Revolution and are widely used to add safety measures to human-robot interaction applicati...

Transference of skills in robotic vs. laparoscopic simulation: a randomized controlled trial.

BACKGROUND: Elucidating how robotic skills are best obtained will enable surgeons to best develop future robotic training programs. We perform a rando...

Rilpivirine plus cobicistat-boosted darunavir as alternative to standard three-drug therapy in HIV-infected, virologically suppressed subjects: Final results of the PROBE 2 trial.

BACKGROUND: Primary analysis at 24 weeks showed that switching to rilpivirine plus darunavir/cobicistat was non-inferior to continuing a standard thre...

An Intervention by and for Transgender Women Living With HIV: Study Protocol for a Two-Arm Randomized Controlled Trial Testing the Efficacy of " to Improve HIV Care Outcomes.

Transgender women (assigned "male" at birth but who do not identify as male) are disproportionately impacted by HIV and experience unique barriers an...

Deep Learning for Prediction of N2 Metastasis and Survival for Clinical Stage I Non-Small Cell Lung Cancer.

Background Preoperative mediastinal staging is crucial for the optimal management of clinical stage I non-small cell lung cancer (NSCLC). Purpose To d...

Detection of Dental Apical Lesions Using CNNs on Periapical Radiograph.

Apical lesions, the general term for chronic infectious diseases, are very common dental diseases in modern life, and are caused by various factors. T...

Effects of oral white willow bark () and intravenous flunixin meglumine on prostaglandin E in healthy dairy calves.

White willow bark (WWB) is commonly used in combination with other medicinal herbs and analgesics to alleviate inflammatory pain in disbudded calves u...

Validation of 3-Space Wireless Inertial Measurement Units Using an Industrial Robot.

Inertial Measurement Units (IMUs) are beneficial for motion tracking as, in contrast to most optical motion capture systems, IMU systems do not requir...

Estimation of current and post-treatment retinal function in chronic central serous chorioretinopathy using artificial intelligence.

Refined understanding of the association of retinal microstructure with current and future (post-treatment) function in chronic central serous chorior...

Intracorporeal Versus Extracorporeal Anastomosis in Robotic Right Colectomy: A Multicenter, Triple-blind, Randomized Clinical Trial.

OBJECTIVE: To determine if minimally invasive right colectomy with intra-corporeal anastomosis improves postoperative recovery compared to extra-corpo...

Systemic inflammatory response in robot-assisted and laparoscopic surgery for colon cancer (SIRIRALS): study protocol of a randomized controlled trial.

BACKGROUND: Robot-assisted surgery is being increasingly adopted in treating colorectal cancer, and the transition from laparoscopic surgery to robot-...

The effects of a sleep robot intervention on sleep, depression and anxiety in adults with insomnia - Study protocol of a randomized waitlist-controlled trial.

Insomnia is a common sleep disorder characterized by difficulties initiating sleep, maintaining sleep and/or early-morning awakenings. Hyperarousal is...

Artificial intelligence applications and cataract management: A systematic review.

Artificial intelligence (AI)-based applications exhibit the potential to improve the quality and efficiency of patient care in different fields, inclu...

Evaluation and Real-World Performance Monitoring of Artificial Intelligence Models in Clinical Practice: Try It, Buy It, Check It.

The pace of regulatory clearance of artificial intelligence (AI) algorithms for radiology continues to accelerate, and numerous algorithms are becomin...

Immediate effects of manual hyperinflation on cardiorespiratory function and sputum clearance in mechanically ventilated pediatric patients: A randomized crossover trial.

BACKGROUND: In developing countries, lower respiratory tract infection is a major cause of death in children, with severely ill patients being admitte...