Public Health & Policy

Clinical Trials

Latest AI and machine learning research in clinical trials for healthcare professionals.

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Showing 761-780 of 6,112 articles

Clinician engagement shapes the impact of AI-based ECG screening for chronic liver disease in primary care.

Artificial intelligence (AI)-based screening tools show promise for early identification of chronic liver disease (CLD), yet their effectiveness in real-world settings may depend on clinician response to AI-generated recommendations. We performed a post hoc analysis of the intervention arm of the pragmatic, cluster-randomized DULCE trial, in which primary care clinicians received electrocardiogram...

May 9 2026 42106573

An optimal Petrov-Galerkin framework for operator networks.

The optimal Petrov-Galerkin formulation to solve partial differential equations (PDEs) recovers the best approximation in a specified finite-dimensional (trial) space with respect to a suitable norm. However, the recovery of this optimal solution is contingent on being able to construct the optimal weighting functions associated with the trial basis. While explicit constructions are available for ...

May 8 2026 42344098
Safety and diagnostic accuracy of large-language model application of PECARN head injury algorithm.

BACKGROUND: Clinical decision algorithms used by clinicians guide evidence-based decisions and actions. Automated tools can help with the adoption and...

May 8 2026 42127532
Development of Models for Predicting the 7-Month Risk of Venous Thromboembolism and Clinically Relevant Bleeding in Ambulatory Patients with Cancer: Analysis from the AVERT Trial.

BACKGROUND: Patients with cancer are at elevated risk of venous thromboembolism (VTE). While primary thromboprophylaxis reduces VTE incidence, it also...

May 8 2026 42107707
Beyond the Mean: A Machine Learning-Based Trend Analysis of CGM Metrics for Improved HbA1C Estimation in Type 2 Diabetes.

BACKGROUND: Hemoglobin A1C (HbA1C) is the gold standard for assessing long-term glycemic control in people with diabetes. Increasing use of continuous...

May 8 2026 42100954
Next-generation probiotics: an outlook into current applications and future developments.

The probiotics field, a historically popular yet scientifically debated discipline, is moving beyond a decades-long promotion of 'first-generation' fo...

May 8 2026 42104000
The geographic digital divide among dementia caregivers in the U.S.: a cross-sectional study.

BACKGROUND: Digital health tools, particularly patient portals, can support caregiving, but there is limited understanding of how sociodemographic and...

May 8 2026 42104368
Machine learning and SHAP interpretation to identify high-level compassion fatigue among operating room nurses: a multicenter cross-sectional study.

BACKGROUND: Operating room nurses (ORNs) are at high risk for compassion fatigue (CF), which significantly impairs individuals' well-being, undermines...

May 8 2026 42104411
Benign-by-design chemistry: Reinventing ligand-based drug design at the edge of AI.

Ligand-based drug design (LBDD) has long driven therapeutic innovation; however, its traditional potency-centered paradigm often oversimplifies biolog...

May 7 2026 42105905
Road traffic accident severity prediction based on large-scale data and multi-dimensional factors: an explainable ensemble learning approach.

Road traffic accidents cause substantial fatalities and economic losses, yet large-scale severity analysis is often constrained by limited access to h...

May 7 2026 42102653
Input-to-State Safety for Reinforcement Learning.

In this article, we present a novel off-policy, safe reinforcement learning (RL) approach for nonlinear dynamical systems under input saturation that ...

May 7 2026 42096385
Global Perspectives on CNS Drug Innovation: Achievements, Barriers, and Priorities for the Next Decade.

BACKGROUND: Over the past decade, neuropsychopharmacology has shifted from stagnation to momentum, with first-in-class mechanisms and biomarker-enable...

May 7 2026 42096531
Physics-informed neural networks for predicting laser-tissue interaction in maxillofacial reconstruction surgery.

This study employs Physics-Informed Neural Networks (PINNs) to simulate the thermal dynamics of biological tissue under laser irradiation by embedding...

May 7 2026 42098182
Financial incentives increase uptake and perceived effectiveness of autonomous medical AI, yet patients still seek human reconfirmation.

Artificial intelligence (AI) is increasingly used for diagnostic screening. In diabetic retinopathy screening, autonomous AI systems can identify dise...

May 7 2026 42098357
Commercial AI for CT lung cancer screening: product capabilities, coverage of nodule management tasks and supporting evidence.

OBJECTIVES: To characterize the capabilities of CE-marked AI products for lung nodule analysis in lung cancer screening (LCS), quantify their coverage...

May 7 2026 42098370
Health AI research capacity and equity-adjusted patient value in 27 European Union countries: an ecological panel study, 2011-2024.

BACKGROUND: Investments in health artificial intelligence (AI) are accelerating across European Union member states, yet evidence linking national AI ...

May 7 2026 42098703
Mechanistically Informed and Omics-Guided Essential Oil Applications for Food Preservation.

The growing demand for safe, sustainable, and clean-label food preservation strategies has accelerated interest in plant-derived essential oils (EOs) ...

May 6 2026 42103286
Real-time artificial intelligence-based needle tracking for ultrasound-guided regional anesthesia training: a pilot prospective randomized controlled trial.

BACKGROUND: Proper needle visualization is a major technical challenge for novices learning ultrasound-guided regional anesthesia (UGRA). We developed...

May 6 2026 42092786
Artificial intelligence in ovarian pathophysiology and management: a systematic review and meta-analysis.

BACKGROUND: The integration of artificial intelligence (AI) into reproductive medicine and gynecologic oncology has driven transformative advances in ...

May 6 2026 42092958
Expanding the Therapeutic Window in Oncology: Modern Strategies and Future Directions.

Background:The enhancement of the therapeutic window (TW) in oncology remains a significant challenge, as the majority of anticancer treatments face d...

May 6 2026 42093176
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