Public Health & Policy

Clinical Trials

Latest AI and machine learning research in clinical trials for healthcare professionals.

5,895 articles
Stay Ahead - Weekly Clinical Trials research updates
Subscribe
Browse Categories
Showing 161-180 of 5,895 articles

Engineering smart polymeric lipid nanoparticles for breast cancer: AI-guided formulation design, biological barriers, and translational constraints.

Breast cancer is a biologically heterogeneous disease in which tumor-intrinsic diversity and the tumor immune microenvironment jointly shape therapeutic resistance and variable clinical outcomes. Although nanomedicine has improved the safety and pharmacokinetic profiles of several anticancer agents, clinically approved nanocarriers have produced limited efficacy gains, partly because of heterogene...

Jun 28 2026 42366415

Dataset distillation for machine learning force field in phase transition regime.

Machine learning force fields (MLFFs) have emerged as powerful data-driven tools for atomistic simulations, enabling large-scale and complex atomic systems to be simulated with accuracy comparable to that of ab initio methods. However, MLFFs often suffer from low training efficiency in the phase transition regime, where structural fluctuations are significantly elevated. To address this challenge,...

Jun 28 2026 42334160
Cognitive gains and addictive losses: The double-edged sword of Generative AI on employee creative thinking.

Drawing on Social Cognitive Theory (SCT), this study examines how Generative Artificial Intelligence (GAI) use is associated with employee creative th...

Jun 27 2026 42364395
CBINN: Cancer Biology-Informed Neural Network for Unknown Parameter Estimation and Missing Physics Identification.

The dynamics of tumor-immune interactions within a complex tumor microenvironment are typically modeled using a system of ordinary differential equati...

Jun 27 2026 42365212
Prompt sensitivity of large language models in orthodontic patient counseling: a scenario-based experimental study.

BACKGROUND: Large language models (LLMs) are increasingly used as accessible sources of health information, including orthodontic patient counseling. ...

Jun 27 2026 42365257
Promising performance of locally deployed large language models for postoperative orthopaedic patient questions: An In Silico analysis.

PURPOSE: Generative artificial intelligence (AI), particularly large language models (LLMs), are increasingly utilised in healthcare. While this may r...

Jun 26 2026 42367364
The Addition of Computer-Aided Detection (CADe) to Texture and Color Enhancement Imaging (TXI) Does Not Improve Adenoma Detection Rate During Colonoscopy: A Prospective Study.

OBJECTIVES: Early detection and resection of colorectal polyps prevent their progression toward advanced adenocarcinomas. The use of Texture and Color...

Jun 26 2026 42363424
A Physics-Informed Deep Learning Framework for Estimating Muscle Activation Patterns Following Achilles Tendon Repair.

Accurate soleus (SOL) activation assessment is essential for Achilles tendon rupture (ATR) recovery, yet direct measurement remains a clinical challen...

Jun 26 2026 42359776
AI-Based Pathology classifier Predicts Sensitivity to Enzalutamide in Metastatic Hormone-Sensitive Prostate Cancer: A Biomarker Analysis of the ENZAMET Trial.

PURPOSE: The ENZAMET trial established that enzalutamide added to androgen deprivation therapy (ADT) improves overall survival (OS) in metastatic horm...

Jun 26 2026 42360803
Large Language Models for Breast and Cervical Cancers Communication: Mixed Methods Evaluation Study Assessing Linguistic Quality, Safety, and Accessibility.

BACKGROUND: Effective communication about breast and cervical cancers remains a public health challenge, with widespread misinformation and barriers t...

Jun 26 2026 42361270
Selecting, Scaling, and Measuring the Value of Ambient AI in a Nonacademic Health System: Multiphase Pilot Study.

BACKGROUND: Most US health systems operate on a local or regional scale and face substantial financial and staffing pressures, which are intensified b...

Jun 26 2026 42361272
Hybrid CQD sensors for food safety: MOF/MIP composites, AI integration, and real-matrix performance.

Carbon quantum dots (CQDs) have emerged as promising photoluminescent nanomaterials for food safety monitoring owing to their tunable optical properti...

Jun 26 2026 42361473
Neural networks and behavioral frameworks to analyse the impact of media and individual awareness for controlling epidemics.

Enhancing individual awareness and immunization are generally recognized as fundamental strategies for controlling infectious diseases. Awareness is i...

Jun 26 2026 42362591
Using generative AI to support clinical reasoning coaching: a theory-informed approach.

Generative artificial intelligence (gen AI) can support and likely enhance clinical reasoning coaching for struggling medical learners when its use is...

Jun 26 2026 42345255
Clinical Risk Management and Patient-safety Research: A Large-scale Bibliometric Mapping of the Field and Its Emerging Directions (Master vs. 2021-2025).

BACKGROUND: To map the evolution, knowledge structure, and emerging directions of clinical risk management (CRM) and patient-safety research by contra...

Jun 26 2026 42350329
Integrated single-cell RNA sequencing and Bulk-RNA technologies reveal the immunological characteristics of lactylation related-genes in glioblastoma.

OBJECTIVE: Glioblastoma (GBM) is the most aggressive type of intracranial malignant tumor, known for its extremely poor prognosis. Lactylation, a newl...

Jun 26 2026 42361107
Personal Health Large Language Models and the Negotiation of Medical Authority in Clinical Care: Opportunities, Risks, and Governance.

Personal health large language models (PH-LLMs) are patient-facing conversational systems that synthesize user-entered information, patient-generated ...

Jun 25 2026 42347687
Metabolic and vascular outcomes after transition to the MiniMed 780G system in adults ≥65 years with type 1 diabetes: a randomised, single-centre study.

AIMS/HYPOTHESIS: Hybrid closed-loop insulin delivery systems are increasingly regarded as the preferred therapy for type 1 diabetes, although evidence...

Jun 25 2026 42347980
Investigating the feasibility and acceptability of the TeleRehabilitation of balance clinical and economic Decision Support System (TeleRehaB DSS) in adults at risk of falls: study protocol for a multicentre clinical trial.

INTRODUCTION: Falls are a significant concern for older adults, particularly those with neurological, vestibular, cognitive and post-viral conditions,...

Jun 25 2026 42350021
Observational multicentre registry to update key interventions and new approaches with artificial intelligence for heart failure (OKINAWA-HF): a retrospective medical record-derived registry study protocol.

INTRODUCTION: The efficacy of guideline-directed medical therapy (GDMT) for heart failure has been established in clinical trials, but trial populatio...

Jun 25 2026 42350022
Browse Categories