Infectious Disease

COVID-19

Latest AI and machine learning research in covid-19 for healthcare professionals.

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Expanding cholera serosurveillance to vaccinated populations

Mass oral cholera vaccination campaigns targeted at subnational areas with high incidence are centra...

nnDoseNet: Intuitive and Flexible Deep Learning Framework to Train and Evaluate Radiotherapy Dose Prediction Models

Radiotherapy (RT) dose optimization is often labor-intensive, requiring repeated manual adjustments ...

Unraveling the drivers of leptospirosis risk in Thailand using machine learning

Leptospirosis poses a significant public health challenge in Thailand, driven by a complex mix of en...

Integration of Deep Learning Annotations with Functional Genomics Improves Identification of Causal Alzheimer’s Disease Variants

Genetic variants associated with Alzheimer’s disease (AD) through genome-wide association studies (G...

Proteome-wide autoantibody screening and holistic autoantigenomic analysis unveil COVID-19 signature of autoantibody landscape

This study presents “aUToAntiBody Comprehensive Database (UT-ABCD)”, a comprehensive catalog of auto...

SyMetrics: An Integrated Machine Learning Model for Evaluating the Pathogenicity of Synonymous Variants in the Human Genome

Synonymous single nucleotide variants (sSNVs), traditionally seen as neutral, are now recognized for...

Reduced Penetrance is Common Among Predicted Loss-of-Function Variants and is Likely Driven by Residual Allelic Activity

Loss-of-function genetic variants (LoFs) often result in severe phenotypes, including autosomal domi...

Suitability of just-in-time adaptive intervention in post-COVID-19-related symptoms: A systematic scoping review

Patients with post-COVID-19-related symptoms require active and timely support in self-management. J...

Federated Learning for the pathogenicity annotation of genetic variants in multi-site clinical settings

Rare diseases collectively affect 5% of the population. However, fewer than 50% of rare disease pati...

Cross-Disorder Machine Learning Uncovers Schizophrenia Risk Variants Predictive of Alzheimer’s Disease

Alzheimer’s disease (AD) and Schizophrenia (SCZ) exhibit overlapping clinical features and biologica...

From Text to Translation: Using Language Models to Prioritize Variants for Clinical Review

Despite rapid advances in genomic sequencing, most rare genetic variants remain insufficiently chara...

Omics-Based Computational Approaches for Biomarker Identification, Prediction, and Treatment of Long COVID

Long COVID, also referred to as post-acute sequelae of COVID-19 (PASC), is a substantial global heal...

Genotyping TOMM40’523 Poly-T Polymorphisms Using Whole-Genome Sequencing

The TOMM40’523 poly-T repeat polymorphism (rs10524523), located in the TOMM40 gene and in linkage di...

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