Infectious Disease

COVID-19

Latest AI and machine learning research in covid-19 for healthcare professionals.

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Showing 5741-5760 of 8,596 articles

Vision-referential speech enhancement of an audio signal using mask information captured as visual data.

This paper describes a vision-referential speech enhancement of an audio signal using mask information captured as visual data. Smartphones and tablet devices have become popular in recent years. Most of them not only have a microphone but also a camera. Although the frame rate of the camera in such devices is very low compared to the audio signal from the microphone, it will be useful to enhance ...

Jan 1 2019 30710939

Outgroup Machine Learning Approach Identifies Single Nucleotide Variants in Noncoding DNA Associated with Autism Spectrum Disorder.

Autism spectrum disorder (ASD) is a heritable neurodevelopmental disorder affecting 1 in 59 children. While noncoding genetic variation has been shown to play a major role in many complex disorders, the contribution of these regions to ASD susceptibility remains unclear. Genetic analyses of ASD typically use unaffected family members as controls; however, we hypothesize that this method does not e...

Jan 1 2019 30864328
An enhanced workflow for variant interpretation in UniProtKB/Swiss-Prot improves consistency and reuse in ClinVar.

Personalized genomic medicine depends on integrated analyses that combine genetic and phenotypic data from individual patients with reference knowledg...

Jan 1 2019 30937429
The 18th FRAME Annual Lecture, October 2019: Human Trials in Pharmacology.

Safety and efficacy testing is a crucial part of the drug development process, and several different methods are used to obtain the necessary data (e....

Jan 1 2019 32090621
Anti-cancer Potential of Captopril and Botulinum Toxin Type-A and Associated p53 Gene Apototic Stimulating Activity.

Mutational inactivation of p53 is a key player in the development of human cancer. Thus, retrieving the tumor suppressor activity of p53 gene is consi...

Jan 1 2019 32184862
ASSOCIATION OF FOXP3 GENE VARIANTS WITH RISK OF HASHIMOTO'S THYROIDITIS AND CORRELATION WITH ANTI-TPO ANTIBODY LEVELS.

CONTEXT: Regulatory T cells (Tregs) have critical roles in preventing autoimmune diseases such as Hashimoto's thyroiditis (HT). Forkhead box P3 (Foxp3...

Jan 1 2019 32377237
Thiazolidinedione Derivative Suppresses LPS-induced COX-2 Expression and NO Production in RAW 264.7 Macrophages.

The present study was designed to investigate the inhibitory effect of 2,4 bis-[(4-ethoxyphenyl)azo] 5-(3-hydroxybenzylidene) thiazolidine-2,4-dione (...

Jan 1 2019 32641947
[Effects of ATP on expression of inflammatory factors in endothelial progenitor cells induced by LPS and the mechanisms].

To investigate the effects of adenosine triphosphate (ATP) on expression of inflammatory factors induced by lipopolysaccharide (LPS) in endothelial pr...

Dec 28 2018 30643045
[The β2GPI/aβ2GPI inhibits phagocytosis of oxidized low-density lipoprotein in THP-1 macrophages via activating TLR4].

Objective To investigate the effects of β2 glycoprotein I/anti-β2 glycoprotein I antibody complex (β2GPI/aβ2GPI) on lipid phagocytosis and class B sca...

Dec 1 2018 30626470
The Comparison Between Different Immunoassays for Serum Carbohydrate Antigen (CA 19-9) Concentration Measurement.

INTRODUCTION: The carbohydrate antigen (CA 19-9) is a marker for pancreatic and colorectal carcinoma. In our study, we have investigated the level of ...

Dec 1 2018 30692705
Platelet mitochondrial cytochrome c oxidase subunit I variants with benzene poisoning.

BACKGROUND: Chronic benzene poisoning (CBP) is one of the most common chronic occupational poisoning which is associated with mitochondrial oxidative ...

Dec 1 2018 30746226
Outcome prediction of intracranial aneurysm treatment by flow diverters using machine learning.

OBJECTIVEFlow diverters (FDs) are designed to occlude intracranial aneurysms (IAs) while preserving flow to essential arteries. Incomplete occlusion e...

Nov 1 2018 30453461
Using Machine Learning-Based Multianalyte Delta Checks to Detect Wrong Blood in Tube Errors.

OBJECTIVES: An unfortunate reality of laboratory medicine is that blood specimens collected from one patient occasionally get mislabeled with identifi...

Oct 24 2018 30169595
Estimating Normal Values of Rare T-Lymphocyte Populations in Peripheral Blood of Healthy Cuban Adults.

INTRODUCTION Flow cytometry allows immunophenotypic characterization of important lymphocyte subpopulations for diagnosis of diseases such as cancer, ...

Oct 1 2018 31242168
GARFIELD-NGS: Genomic vARiants FIltering by dEep Learning moDels in NGS.

SUMMARY: Exome sequencing approach is extensively used in research and diagnostic laboratories to discover pathological variants and study genetic arc...

Sep 1 2018 29668842
A deep learning based segregation algorithm to increase speech intelligibility for hearing-impaired listeners in reverberant-noisy conditions.

Recently, deep learning based speech segregation has been shown to improve human speech intelligibility in noisy environments. However, one important ...

Sep 1 2018 30424625
Multivariate Pattern Analysis of Genotype-Phenotype Relationships in Schizophrenia.

Genetic risk variants for schizophrenia have been linked to many related clinical and biological phenotypes with the hopes of delineating how individu...

Aug 20 2018 29534239
[From symptom to syndrome using modern software support].

Diagnosing rare diseases can be challenging for clinicians. This article gives an overview on novel approaches, which enable automated phenotype-drive...

Aug 1 2018 29995249
Enhancing fluorescent protein photostability through robot-assisted photobleaching.

Improving fluorescent proteins through the use of directed evolution requires robust techniques for screening large libraries of genetic variants. Her...

Jul 16 2018 29897363
Machine-learned analysis of the association of next-generation sequencing-based human TRPV1 and TRPA1 genotypes with the sensitivity to heat stimuli and topically applied capsaicin.

Heat pain and its modulation by capsaicin varies among subjects in experimental and clinical settings. A plausible cause is a genetic component, of wh...

Jul 1 2018 29596157
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