Cardiovascular

Dyslipidemia

Latest AI and machine learning research in dyslipidemia for healthcare professionals.

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Serum sclerostin as a marker of microvascular and macrovascular complications among children and adolescents with type 1 diabetes mellitus.

BACKGROUND: Uncontrolled diabetes mellitus (DM) accelerates atherosclerosis and vascular diseases, l...

Iron-dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP-1 monocytes.

Atherosclerosis leading to cardiovascular diseases remains a dominant medical problem. In the early ...

Switching Therapy to the Second Brand of Generic Atorvastatin: A 6-Month Retrospective Cohort, Real-World Study.

INTRODUCTION: High levels of low-density lipoprotein-cholesterol (LDL) is a major risk factor for ca...

Preoperative BOLD cerebrovascular reactivity correlates with intraoperative STA-MCA bypass flow and influences postoperative CVR improvement.

INTRODUCTION: The superficial temporal artery-middle cerebral artery (STA-MCA) flow augmentation byp...

Hemostatic Activation Markers and Early Neurological Deterioration in Branch Atheromatous Disease-Related Stroke.

AIMS: Branch atheromatous disease (BAD)-related stroke, caused by atherosclerotic occlusion at the o...

Restoring AIBP expression in the retina provides neuroprotection in glaucoma.

Glaucoma is a neurodegenerative disease manifested by retinal ganglion cell (RGC) death and irrevers...

Reduced blood EPAC1 protein levels as a marker of severe coronary artery disease: the role of hypoxic foam cell-transformed smooth muscle cells.

BACKGROUND: Vascular smooth muscle cells loaded with cholesterol (foam-VSMCs) play a crucial role in...

Mechanisms and Applications of Apolipoproteins and Apolipoprotein Mimetic Peptides: Common Pathways in Cardiovascular Disease and Cancer.

Apolipoproteins are the defining functional component of lipoproteins and play critical roles in lip...

IDENTIFYING A SEPSIS SUBPHENOTYPE CHARACTERIZED BY DYSREGULATED LIPOPROTEIN METABOLISM USING A SIMPLIFIED CLINICAL DATA ALGORITHM.

Background: Cholesterol metabolism is dysregulated in sepsis contributing to patient heterogeneity. ...

Nuciferine activates intestinal TAS2R46 to attenuate metabolic disorders and hyperlipidemia via hepatic VLDL regulation.

BACKGROUND: Dysregulated blood lipid metabolism, a primary driver of hyperlipidemia, is closely asso...

Transfer learning of multicellular organization via single-cell and spatial transcriptomics.

Biological tissues exhibit complex gene expression and multicellular patterns that are valuable to d...

Machine Learning-Based Prediction of Unplanned Readmission Due to Major Adverse Cardiac Events Among Hospitalized Patients with Blood Cancers.

BackgroundHospitalized patients with blood cancer face an elevated risk for cardiovascular diseases ...

Machine learning-based prediction of LDL cholesterol: performance evaluation and validation.

OBJECTIVE: This study aimed to validate and optimize a machine learning algorithm for accurately pre...

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