Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Showing 316-336 of 11,636 articles
Integrated single-cell transcriptomics, Mendelian randomization, and machine learning identify CEBPZ as an immune-related biomarker in oral lichen planus.

BACKGROUND: Oral lichen planus (OLP) is a chronic, immune-mediated oral mucosal disease with complex...

Sep 2026 42735428
Machine learning-based identification of core regulatory targets in 1-nitropyrene-induced placental trophoblast dysfunction and FGR.

1-NP (1-Nitropyrene), a nitrated polycyclic aromatic hydrocarbon derived from diesel combustion, is ...

(1)
Sep 2026 42735479
Sequence optimization targeting mRNA stability enhances monoclonal antibody titers in CHO cells.

This study presents a DNA sequence optimization approach that integrates mRNA stability as a tunable...

(4)
Sep 2026 42735877
An engineered nanopore identifies saccharides, amino acids, peptides and ribonucleotides.

Simultaneous characterization of proteins, RNAs and glycans with a nanopore remains a substantial ch...

(1)
Sep 2026 42736414
Therapeutic cancer vaccines: development, challenges, and future perspectives.

Therapeutic cancer vaccines are designed to induce tumor-specific immunity and durable antitumor sur...

(2)
Sep 2026 42736453
InsightRP2-An Interdisciplinary Approach Toward Therapy Development in RP2-Associated Retinopathy.

Advancing the development of specific gene therapies for rare genetic eye disorders is a major chall...

(2)
Sep 2026 42740453
The machine-learning classifier ALLCatchR2 identifies 20 T-ALL subtypes across cohorts and age groups.

T-cell acute lymphoblastic leukemia (T-ALL) comprises molecularly diverse subtypes, but robust cross...

(1)
Sep 2026 42741738
Nipah virus in the era of global connectivity: molecular evolution, transmission risk, and preparedness strategies.

Nipah virus (NiV) is a highly pathogenic zoonotic RNA virus belonging to the genus Henipavirus withi...

(1)
Sep 2026 42732490
Overcoming cancer resistance in pancreatic cancer: toward dynamic precision oncology.

Pancreatic ductal adenocarcinoma (PDAC) remains a highly lethal malignancy, largely because of its p...

Sep 2026 42730833
Multi-omics analysis and experiments reveal an association between polystyrene microplastics exposure and colorectal cancer progression.

BACKGROUND: Microplastics have emerged as environmental contaminants, yet their potential role in co...

(2)
Sep 2026 42731388
Detection of antibiotic heteroresistance in clinical microbiology: current and emerging methodologies.

BACKGROUND: Antibiotic heteroresistance (HR) is characterised by the coexistence of susceptible and ...

(2)
Sep 2026 42731626
The Landmark Series: Mutation-Based Therapy of Pancreatic Cancer.

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) remains a highly lethal malignancy with limited ...

(3)
Sep 2026 42732021
Structural evolution of ionizable lipids for nucleic acid delivery.

Ionizable lipid nanoparticles have emerged as a potent non-viral delivery platform for nucleic acid ...

(1)
Sep 2026 42728430
High-Throughput Technologies for Targeted Covalent Drug Discovery: Recent Advances and Perspectives.

Covalent drugs have attracted increasing attention in modern drug discovery because of their prolong...

(2)
Sep 2026 42725532
DNA methylation biomarkers for early detection of ovarian cancer.

Ovarian cancer (OC) remains difficult to detect at an early stage, and current screening approaches ...

(3)
Sep 2026 42726150
BeitAI-pHLA: Multiallele Peptide-HLA Class I Binding Prediction Using Protein Language Model and Multi-Instance Learning.

Human leukocyte antigen (HLA) molecules participate in cellular immune responses by binding to pepti...

(2)
Sep 2026 42729647
Genomic language model for predicting enhancers and their allele-specific activity in the human genome.

MOTIVATION: Predicting and deciphering the regulatory logic of enhancers remains a significant chall...

(1)
Sep 2026 42723633
UCResponNet-X: cross-platform multi-dataset gene expression for predictive modeling of drug response in ulcerative colitis.

Predictive modeling of biologic drug response using transcriptomic data is challenged by strong plat...

(2)
Sep 2026 42717746
Decoding gene regulation in plant genomes with artificial intelligence.

One of the central goals of plant functional genomics is to uncover regulatory mechanisms that shape...

Sep 2026 42717834
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