Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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MSIpred: a python package for tumor microsatellite instability classification from tumor mutation annotation data using a support vector machine.

Microsatellite instability (MSI) is characterized by high degree of polymorphism in microsatellite l...

Genotoxicity evaluation of titanium dioxide nanoparticles using the mouse lymphoma assay and the Ames test.

Titanium dioxide nanoparticles (TiO-NPs) are widely used in the cosmetics, health, and food industri...

Label-Free Pathogen Detection by a Deoxyribozyme Cascade with Visual Signal Readout.

A colorimetric nucleic acid based test for label-free pathogen detection has been developed and used...

Deep learning identifies genome-wide DNA binding sites of long noncoding RNAs.

Long noncoding RNAs (lncRNAs) can exert their function by interacting with the DNA via triplex struc...

RNA3DCNN: Local and global quality assessments of RNA 3D structures using 3D deep convolutional neural networks.

Quality assessment is essential for the computational prediction and design of RNA tertiary structur...

A primer on deep learning in genomics.

Deep learning methods are a class of machine learning techniques capable of identifying highly compl...

A versatile assay for alkaline phosphatase detection based on thymine-Hg-thymine structure generation mediated by TdT.

Alkaline phosphatase (ALP) is a vital hydrolysis enzyme in phosphate metabolism, which catalyzes the...

Deleterious Non-Synonymous Single Nucleotide Polymorphism Predictions on Human Transcription Factors.

Transcription factors (TFs) are the major components of human gene regulation. In particular, they b...

Machine Learning Methods as a Tool for Predicting Risk of Illness Applying Next-Generation Sequencing Data.

Next-generation sequencing (NGS) data present an untapped potential to improve microbial risk assess...

Changes in the expression of four ABC transporter genes in response to imidacloprid in Bemisia tabaci Q (Hemiptera: Aleyrodidae).

Bemisia tabaci (Gennadius) (Hemiptera: Aleyrodidae), a globally invasive species complex that causes...

Computational prediction of inter-species relationships through omics data analysis and machine learning.

BACKGROUND: Antibiotic resistance and its rapid dissemination around the world threaten the efficacy...

Gene Ontology-based function prediction of long non-coding RNAs using bi-random walk.

BACKGROUND: With the development of sequencing technology, more and more long non-coding RNAs (lncRN...

Bi-stream CNN Down Syndrome screening model based on genotyping array.

BACKGROUND: Human Down syndrome (DS) is usually caused by genomic micro-duplications and dosage imba...

Deep learning architectures for prediction of nucleosome positioning from sequences data.

BACKGROUND: Nucleosomes are DNA-histone complex, each wrapping about 150 pairs of double-stranded DN...

Deepbinner: Demultiplexing barcoded Oxford Nanopore reads with deep convolutional neural networks.

Multiplexing, the simultaneous sequencing of multiple barcoded DNA samples on a single flow cell, ha...

Laplacian regularized low-rank representation for cancer samples clustering.

Cancer samples clustering based on biomolecular data has been becoming an important tool for cancer ...

Evaluation of the bias and precision of regression techniques and machine learning approaches in total dissolved solids modeling of an urban aquifer.

TDS is modeled for an aquifer near an unlined landfill in Canada. Canadian Drinking Water Guidelines...

Multi-Objective Genetic Algorithm Assisted by an Artificial Neural Network Metamodel for Shape Optimization of a Centrifugal Blood Pump.

A centrifugal blood pump is a common type of the pump used as a left ventricular assist device (LVAD...

Molecular prevalence of parvovirus B19 among HIV1-infected patients in Iran.

Different outcomes of parvovirus B19 (B19V) infection in immunocompromised patients, including HIV1...

An open-source k-mer based machine learning tool for fast and accurate subtyping of HIV-1 genomes.

For many disease-causing virus species, global diversity is clustered into a taxonomy of subtypes wi...

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