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Subcategories: Genetics

Showing 5524-5544 of 11,138 articles

In Silico Prediction of O⁶-Methylguanine-DNA Methyltransferase Inhibitory Potency of Base Analogs with QSAR and Machine Learning Methods.

O⁶-methylguanine-DNA methyltransferase (MGMT), a unique DNA repair enzyme, can confer resistance to ...

Nov 2018 30404161

Introducing Heuristic Information Into Ant Colony Optimization Algorithm for Identifying Epistasis.

Epistasis learning, which is aimed at detecting associations between multiple Single Nucleotide Poly...

Nov 2018 30403637

Anti-microbial and anti-mycotoxigenic activities of endophytic isolated from (L.) G. Don.: molecular characterisation and bioactive compound isolation.

The present study investigated the anti-microbial and anti-mycotoxigenic activities of the ethyl ace...

Nov 2018 30834151

Nucleotide and structural label identification in single RNA molecules with quantum tunneling spectroscopy.

Although a number of advances have been made in RNA sequencing and structural characterization, the ...

Nov 2018 30774901

A deep learning approach to automate refinement of somatic variant calling from cancer sequencing data.

Cancer genomic analysis requires accurate identification of somatic variants in sequencing data. Man...

Nov 2018 30397337

Generalized multifactor dimensionality reduction approaches to identification of genetic interactions underlying ordinal traits.

The manifestation of complex traits is influenced by gene-gene and gene-environment interactions, an...

Nov 2018 30387901

On String Languages Generated by Spiking Neural P Systems With Structural Plasticity.

Spiking neural P systems (SNP systems) are parallel and non-deterministic models of computation, ins...

Nov 2018 30403634

LogLoss-BERAF: An ensemble-based machine learning model for constructing highly accurate diagnostic sets of methylation sites accounting for heterogeneity in prostate cancer.

Although modern methods of whole genome DNA methylation analysis have a wide range of applications, ...

Nov 2018 30388122

Effective feature learning and fusion of multimodality data using stage-wise deep neural network for dementia diagnosis.

In this article, the authors aim to maximally utilize multimodality neuroimaging and genetic data fo...

Nov 2018 30381863

Biohydrogen production under hyper salinity stress by an anaerobic sequencing batch reactor with mixed culture.

BACKGROUND: This study investigated the effect of organic loading rate (OLR) and NaCl concentration ...

Nov 2018 30728988

Large-Scale Multi-Class Image-Based Cell Classification With Deep Learning.

Recent advances in ultra-high-throughput microscopy have enabled a new generation of cell classifica...

Oct 2018 30387753

Gene Essentiality Analyzed by Transposon Mutagenesis and Machine Learning in a Stable Haploid Isolate of .

Knowing the full set of essential genes for a given organism provides important information about wa...

Oct 2018 30377286

Role of Electrostatic Interactions on Supramolecular Organization in Calf-Thymus DNA Solutions under Flow.

Previous investigations were conducted on two concentrations of DNA solution: 4 mg/mL, for which it ...

Oct 2018 30961129

Automated detection of cancer cells in effusion specimens by DNA karyometry.

BACKGROUND: The average sensitivity of conventional cytology for the identification of cancer cells ...

Oct 2018 30339327

Ensemble of machine learning algorithms using the stacked generalization approach to estimate the warfarin dose.

Warfarin dosing remains challenging due to narrow therapeutic index and highly individual variabilit...

Oct 2018 30339708

Drug Repurposing Prediction for Immune-Mediated Cutaneous Diseases using a Word-Embedding-Based Machine Learning Approach.

Immune-mediated diseases affect more than 20% of the population, and many autoimmune diseases affect...

Oct 2018 30342048

Machine learning and structural analysis of Mycobacterium tuberculosis pan-genome identifies genetic signatures of antibiotic resistance.

Mycobacterium tuberculosis is a serious human pathogen threat exhibiting complex evolution of antimi...

Oct 2018 30333483

Multivariate machine learning models for prediction of pathologic response to neoadjuvant therapy in breast cancer using MRI features: a study using an independent validation set.

PURPOSE: To determine whether a multivariate machine learning-based model using computer-extracted f...

Oct 2018 30328048

Structure and Protein Interaction-Based Gene Ontology Annotations Reveal Likely Functions of Uncharacterized Proteins on Human Chromosome 17.

Understanding the function of human proteins is essential to decipher the molecular mechanisms of hu...

Oct 2018 30265558

Recurrent Neural Network for Predicting Transcription Factor Binding Sites.

It is well known that DNA sequence contains a certain amount of transcription factors (TF) binding s...

Oct 2018 30323198

Deep-RBPPred: Predicting RNA binding proteins in the proteome scale based on deep learning.

RNA binding protein (RBP) plays an important role in cellular processes. Identifying RBPs by computa...

Oct 2018 30323214