Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Showing 6931-6951 of 11,181 articles
Altered cerebral functional activity and its associated genetic profiles underlying chronic insomnia disorder before and after treatment.

OBJECTIVES: The resting-state cerebral functional activity underlying chronic insomnia disorder (CID...

Jun 2025 40384005
Characterization of ROMK cellular heterogeneity along the mouse kidney thick ascending limb.

The renal thick ascending limb (TAL) plays a key role in water and ion homeostasis. Apical potassium...

Jun 2025 40358700
Drug-Drug interactions and special considerations in breast cancer patients treated with CDK4/6 inhibitors: A comprehensive review.

Cyclin-dependent kinase 4/6 inhibitors (CDK4/6i) have reshaped the treatment paradigm of hormone rec...

Jun 2025 40367730
Exploring the link between grandmaternal air pollution exposure and Grandchild's ASD risk: A multigenerational population-based study in California.

BACKGROUND: Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder with increasing prevalen...

Jun 2025 40378475
Ceasing sampling at wastewater treatment plants where viral dynamics are most predictable.

Wastewater sampling has been shown to be an effective tool for monitoring the dynamics of an infecti...

Jun 2025 40398086
AutoFE-Pointer: Auto-weighted feature extractor based on pointer network for DNA methylation prediction.

DNA methylation is a critical epigenetic modification that plays a central role in gene regulation, ...

Jun 2025 40339839
m6A-SPP: Identification of RNA N6-methyladenosine modification sites through multi-source biological features and a hybrid deep learning architecture.

The N6-methyladenosine(m6A) modification plays crucial regulatory roles in various biological proces...

Jun 2025 40449782
Predicting Mutation-Disease Associations Through Protein Interactions Via Deep Learning.

Disease is one of the primary factors affecting life activities, with complex etiologies often influ...

Jun 2025 40031830
CR-deal: Explainable Neural Network for circRNA-RBP Binding Site Recognition and Interpretation.

circRNAs are a type of single-stranded non-coding RNA molecules, and their unique feature is their c...

Jun 2025 40146403
Deep Learning-Enhanced Hand-Driven Microfluidic Chip for Multiplexed Nucleic Acid Detection Based on RPA/CRISPR.

The early detection of high-risk human papillomavirus (HR-HPV) is crucial for the assessment and imp...

Jun 2025 40163382
Immunohistochemistry and machine learning study of DNA replication-associated proteins in uterine epithelial tumors and precursor lesions.

Endometrioid adenocarcinoma (EA) has been on the increase in recent years in developed countries. Ea...

Jun 2025 40220589
Deep learning and genomic best linear unbiased prediction integration: An approach to identify potential nonlinear genetic relationships between traits.

Genomic prediction (GP) aims to predict the breeding values of multiple complex traits, usually assu...

Jun 2025 40252763
Pathway Enrichment-Based Unsupervised Learning Identifies Novel Subtypes of Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma.

Existing single-cell clustering methods are based on gene expressions that are susceptible to dropou...

Jun 2025 40272703
GeneDX-PBMC: An adversarial autoencoder framework for unlocking Alzheimer's disease biomarkers using blood single-cell RNA sequencing data.

OBJECTIVE: To identify blood-based biomarkers and therapeutic targets for Alzheimer's disease (AD) b...

Jun 2025 40311462
[Rapid identification and analysis of hemoglobin isoelectric focusing electrophoresis images based on deep learning].

Gel electrophoresis is used to separate and analyze macromolecules (such as DNA, RNA, and proteins) ...

Jun 2025 40394749
Machine Learning-Assisted Analysis of the Oral Cancer Immune Microenvironment: From Single-Cell Level to Prognostic Model Construction.

Oral cancer is among the most prevalent malignant tumours worldwide; prognosis can be affected by se...

Jun 2025 40457149
DRBP-EDP: classification of DNA-binding proteins and RNA-binding proteins using ESM-2 and dual-path neural network.

Regulation of DNA or RNA at the transcriptional, post-transcriptional, and translational levels are ...

Jun 2025 40391089
Learning to utilize internal protein 3D nanoenvironment descriptors in predicting CRISPR-Cas9 off-target activity.

Despite advances in determining the factors influencing cleavage activity of a CRISPR-Cas9 single gu...

Jun 2025 40401239
Digenic variant interpretation with hypothesis-driven explainable AI.

The digenic inheritance hypothesis holds the potential to enhance diagnostic yield in rare diseases....

Jun 2025 40160220
Improving prediction of bacterial sRNA regulatory targets with expression data.

Small regulatory RNAs (sRNAs) are widespread in bacteria. However, characterizing the targets of sRN...

Jun 2025 40342837
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