Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Gene finding revisited: improved robustness through structured decoding from learned embeddings

Gene finding is the task of identifying the locations of coding sequences within the vast amount o...

Adversarial Attacks in Multimodal Systems: A Practitioner's Survey

The introduction of multimodal models is a huge step forward in Artificial Intelligence. A single ...

scMUSCL: multi-source transfer learning for clustering scRNA-seq data.

MOTIVATION: Single-cell RNA sequencing (scRNA-seq) analysis relies heavily on effective clustering t...

May 2025 40152244
Uncovering Population PK Covariates from VAE-Generated Latent Spaces

Population pharmacokinetic (PopPK) modelling is a fundamental tool for understanding drug behaviou...

DNAZEN: Enhanced Gene Sequence Representations via Mixed Granularities of Coding Units

Genome modeling conventionally treats gene sequence as a language, reflecting its structured motif...

Scalable Genomic Context Analysis with GCsnap2 on HPC Clusters

GCsnap2 Cluster is a scalable, high performance tool for genomic context analysis, developed to ov...

Quantum-Enhanced Classification of Brain Tumors Using DNA Microarray Gene Expression Profiles

DNA microarray technology enables the simultaneous measurement of expression levels of thousands o...

Bayesian Forensic DNA Mixture Deconvolution Using a Novel String Similarity Measure

Mixture interpretation is a central challenge in forensic science, where evidence often contains c...

Current Diagnosing Strategies for Mycobacterium tuberculosis and its Drug Resistance: A Review.

Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), remains a major global health threat,...

May 2025 40343775
Fast and Low-Cost Genomic Foundation Models via Outlier Removal

To address the challenge of scarce computational resources in genomic modeling, we introduce GERM,...

Unraveling the three-dimensional genome structure using machine learning.

The study of chromatin interactions has advanced considerably with technologies such as high-through...

May 2025 40058875
Unsupervised Deep Learning for Blood-Brain Barrier Leakage Detection in Diffuse Glioma Using Dynamic Contrast-enhanced MRI.

Purpose To develop an unsupervised deep learning framework for generalizable blood-brain barrier lea...

May 2025 40172325
Identifying the DNA methylation preference of transcription factors using ProtBERT and SVM.

Transcription factors (TFs) can affect gene expression by binding to certain specific DNA sequences....

May 2025 40359430
Decoupled GNNs based on multi-view contrastive learning for scRNA-seq data clustering.

Clustering is pivotal in deciphering cellular heterogeneity in single-cell RNA sequencing (scRNA-seq...

May 2025 40366859
MMsurv: a multimodal multi-instance multi-cancer survival prediction model integrating pathological images, clinical information, and sequencing data.

Accurate prediction of patient survival rates in cancer treatment is essential for effective therape...

May 2025 40366860
GAEDGRN: reconstruction of gene regulatory networks based on gravity-inspired graph autoencoders.

Reconstructing high-resolution gene regulatory networks (GRNs) based on single-cell RNA sequencing d...

May 2025 40415678
Machine learning-augmented m6A-Seq analysis without a reference genome.

Methylated RNA m6A immunoprecipitation sequencing (m6A-Seq) is a powerful technique for investigatin...

May 2025 40415679
Rhythm profiling using COFE reveals multi-omic circadian rhythms in human cancers in vivo.

The study of ubiquitous circadian rhythms in human physiology requires regular measurements across t...

May 2025 40424435
scaLR: a low-resource deep neural network-based platform for single cell analysis and biomarker discovery.

Single-cell ribonucleic acid (RNA) sequencing (scRNA-seq) produces vast amounts of individual cell p...

May 2025 40439670
PLM-DBPs: enhancing plant DNA-binding protein prediction by integrating sequence-based and structure-aware protein language models.

DNA-binding proteins (DBPs) play a crucial role in gene regulation, development, and environmental r...

May 2025 40439671
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