Latest AI and machine learning research in genetics for healthcare professionals.
Pancreatic ductal adenocarcinoma (PDAC) lacks reliable prognostic biomarkers. RNA-based signatures s...
Transcription factors (TFs) regulate gene expression by binding to short, specific DNA sequences, kn...
Acute myeloid leukemia (AML) is a hematological cancer characterized by genetic diversity and poor c...
Genomic best linear unbiased prediction (GBLUP) is widely used for genomic selection in livestock an...
Cells must adopt flexible regulatory strategies to make decisions regarding their fate, including di...
Cystic Fibrosis (CF) and Primary Ciliary Dyskinesia (PCD) are both inherited respiratory disorders t...
Therapeutic progress in glioma, one of the most lethal human cancers, has been limited by molecular ...
DNA language models (DNA-LMs) are transforming how genomic sequence information is represented and i...
Gene expression is governed by both linear DNA sequence and three-dimensional (3D) chromatin archite...
Pathogenic mutations in Leucine-rich repeat kinase 2 (LRRK2) are the predominant genetic cause of Pa...
Mechanistic understanding of how gene activity is regulated has focussed on the roles of transcripti...
We propose strategies for incorporating the information in large language models (LLMs) into statist...
Predicting how DNA sequence specifies gene expression remains a core challenge across regulatory gen...
This work introduces a modular, open-source computational pipeline for glioblastoma (GBM) vaccine de...
Predicting cellular responses to perturbations is essential for understanding gene regulation and ad...
Characterizing tissue-specific (TSp) gene expression is crucial for understanding development and di...
Accurate genome annotation remains a bottleneck in plants, where polyploidy and repeat-rich sequence...
Chromatin accessibility profiling is an important tool for understanding gene regulation and cellula...
Understanding protein sequence-to-function relationship is crucial to assist studies of genetic dise...
RNA plays vital roles in diverse biological processes, thus drawing much attention as potential ther...
Programmable control of gene expression in specific cell types is essential for both basic discovery...