Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Transcriptomic analysis and machine learning have identified shared diagnostic genes and a possible mechanism linking bipolar disorder and epilepsy.

It is well known that bipolar disorder (BD) and epilepsy (EP) are common neurological diseases. The ...

Mar 2026 41790636
The DNA-Based Disease Diagnosis Model with Strand Displacement Reaction.

MicroRNAs (miRNAs) serve as crucial biomarkers in disease diagnosis. Although silicon-based electron...

Mar 2026 41790822
Cell-free DNA methylome and fragmentome analysis for relapse monitoring of Ewing sarcoma.

Liquid biopsies and cell-free DNA (cfDNA) offer minimally invasive methods for the diagnosis and mon...

Mar 2026 41792463
Integrative multi-omics and machine learning identify mitochondrial biomarkers for pathogen-specific sepsis stratification and translational prioritization.

BACKGROUND: Sepsis is a leading cause of critical illness and mortality, yet substantial heterogenei...

Mar 2026 41792770
From tests to truth: A misclassification-aware machine learning framework for estimating brucellosis seroprevalence in wild canids.

Brucellosis is an important zoonotic disease affecting humans, livestock, and wildlife, yet prevalen...

Mar 2026 41790615
PAH-former: Transfer learning for efficient discovery of pulmonary arterial hypertension-associated genes.

BACKGROUND AND AIMS: Pulmonary arterial hypertension (PAH) is a severe disease with limited effectiv...

Mar 2026 41790620
MoGraphDRP: Multi-omics and graph fusion with bilinear attention for predicting drug sensitivity.

Accurate prediction of drug response in cancer cells is a fundamental step toward achieving precisio...

Mar 2026 41790794
Neuroimaging insights into the neurophysiological subtypes of major depressive disorder.

Major depressive disorder (MDD) is a highly heterogeneous condition that limits the reliability of s...

Mar 2026 41794061
Clinical application progress and prospects of non-invasive preimplantation genetic testing (niPGT): A review.

Preimplantation genetic testing (PGT) is a critical tool in reproductive medicine for selecting gene...

Mar 2026 41794367
Automated interpretable artificial intelligence genomic prediction with AIGP.

Predicting phenotypes from genomic mutations remains a major genetic challenge. Traditional statisti...

Mar 2026 41786603
Functional Data Strengthen Clinical Validation of PhenoScore Phenotype-Guided AI for ANKRD11 Missense Variants.

KBG syndrome (KBGS, OMIM #148050) is a rare genetic disorder caused by heterozygous truncating or mi...

Mar 2026 41786677
DiNovo enables high-coverage and high-confidence de novo peptide sequencing via mirror proteases and deep learning.

Despite the recent advancements driven by deep learning, de novo peptide sequencing is still constra...

Mar 2026 41786727
A data-centric approach to detecting and mitigating demographic bias in pediatric mental health text.

BACKGROUND: Healthcare Artificial Intelligence (AI) offers transformative potential but often inheri...

Mar 2026 41786897
Pseudohypoxia and Family History Are Key Predictors of Severe Outcomes in Hereditary Pheochromocytoma and Paraganglioma Syndromes.

OBJECTIVE: Pheochromocytoma and paraganglioma (PPGL) have high genetic predisposition rates. In this...

Mar 2026 41783997
A simulation-based deep learning framework for spatially explicit malaria modeling of CRISPR suppression gene drive mosquitoes.

Engineered CRISPR gene drives are a promising new strategy for fighting malaria and other vector-bor...

Mar 2026 41890961
Critical evaluation of the theory and practice of feed-forward neural networks for genomic prediction.

Genomic prediction (GP) has catalyzed increased rates of genetic gain in animal and plant breeding. ...

Mar 2026 41442545
Maternal Gut Microbiome as a Predictor of Insulin Therapy Requirement in Gestational Diabetes.

BACKGROUND: Gestational diabetes mellitus (GDM) often requires pharmacological intervention beyond l...

Mar 2026 41777157
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