Latest AI and machine learning research in hematology for healthcare professionals.
BACKGROUND: Both in clinical practice and translational research, cell differentiation of leukocytes provides important diagnostic information and insights into pathophysiological mechanisms. The current gold-standard method for bronchoalveolar lavage fluid (BALF) analysis involves histochemical staining of cytospins, followed by manual morphological quantification. This approach however is labor-...
Hypertension is a modifiable risk factor for cardiovascular disease (CVD) and its prevalence is high in the United States and worldwide. Adequate characterization of blood pressure (BP) is essential for the diagnosis and management of hypertension. However, BP assessment can be challenging because of the unique influences across the lifespan, disease conditions, and physical environmental context....
BACKGROUND: The management of type 2 diabetes requires sustained self-management across diet, physical activity, medication adherence, and blood gluco...
Single-cell mechanical profiling of deformations has become a promising method of identifying a functional biomarker in patients with blood cancers. B...
Dry eye disease (DED) is a multifactorial ocular disorder with high prevalence among global population, characterized by tear film instability, hypero...
Red blood cell distribution width (RDW)-derived indicators have increasingly been recognized as biomarkers reflecting systemic inflammation and hemato...
BACKGROUND: This study aimed to develop and internally validate an explainable machine-learning model using routinely available clinicopathologic and ...
BACKGROUND: Diabetic retinopathy (DR) is a leading cause of vision loss, yet conventional retinal screening remains costly and resource-intensive. Thi...
BACKGROUND: Machine-learning models based on tissue transcriptomic data are powerful tools for disease classification. However, their clinical adoptio...
The organ- and stage-specific diversity of megakaryocytes (MKs) has prompted a reassessment of their distribution and functions. By integrating single...
Immune cell engineering has emerged as a transformative frontier in medicine, reshaping therapeutic strategies for cancer, autoimmunity and infectious...
BACKGROUND: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease influenced by multiple genetic and environmental factors.. This study u...
BACKGROUND: Periprosthetic joint infection (PJI) remains one of the most serious complications after joint arthroplasty, and accurate diagnosis contin...
BACKGROUND: The white blood cell-to-hemoglobin ratio (WHR) is a composite biomarker of inflammation and nutrition, but its prognostic role in critical...
Monoclonal proteins (M-proteins) serve as critical biomarkers for plasma cell dyscrasias, yet their unique physicochemical properties paradoxically co...
BACKGROUND: Ambient artificial intelligence scribes are increasingly integrated into electronic health records to reduce documentation burden, but lim...
BACKGROUND: While the single-point insulin sensitivity estimator (SPISE) shows promise as an insulin resistance biomarker, its association with cardio...
BACKGROUND: Patients with cancer are at elevated risk of venous thromboembolism (VTE). While primary thromboprophylaxis reduces VTE incidence, it also...
BACKGROUND: Hemoglobin A1C (HbA1C) is the gold standard for assessing long-term glycemic control in people with diabetes. Increasing use of continuous...
BACKGROUND: Ambulatory blood pressure monitoring (ABPM) plays an irreplaceable role in the diagnosis and management of hypertension. However, more tha...