Hematology

Latest AI and machine learning research in hematology for healthcare professionals.

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Development and validation of a nomogram for predicting advanced chronic kidney disease.

The objective of this study was to develop and validate a nomogram for predicting advanced chronic kidney disease (CKD) through the utilization of routine clinical parameters. To achieve this, we integrated internal and external datasets, employed LASSO and logistic regression to identify independent predictors of advanced CKD for nomogram construction, conducted Bootstrap validation on the traini...

Apr 4 2026 42100739

Artificial intelligence in orthopedics: current applications, challenges, and future directions.

BACKGROUND: Artificial intelligence research in orthopedics has grown rapidly, yet a substantial gap remains between technical development and clinical translation. This narrative review summarizes current applications of artificial intelligence in orthopedic practice and highlights barriers to implementation. MAIN BODY: Current work converges on three domains: machine learning for structured peri...

Apr 3 2026 41933417
Machine learning in the prediction of liver iron concentration and iron chelation therapy adjustment.

OBJECTIVES: Iron chelation therapy titration is managed by hematologists who monitor iron levels and adjust medication dosages to achieve patient outc...

Apr 2 2026 41925003
An explainable online frailty prediction model for community-dwelling older adults based on machine learning algorithms: a cross-sectional study based on retrospective health data.

BACKGROUND: Frailty is a significant health concern associated with diminished physiological reserves and increased healthcare burdens. Currently, eff...

Apr 2 2026 41924849
Constructing a corpus of hematologic pathology notes for the fine-tuning of BERT models for named entity recognition.

BACKGROUND: Microscopic, immunologic, and chemical testing play a major role in the diagnostic process of hematologic cancer patients. Pathologists re...

Apr 2 2026 41930825
Exploratory prediction model for deep vein thrombosis in intensive care patients after anticoagulation therapy: An observational study.

BACKGROUND: Despite low-molecular-weight heparin (LMWH) prophylaxis, the incidence of deep vein thrombosis (DVT) remains high in intensive care unit (...

Apr 2 2026 41932233
Predicting one-year mortality risk in ICU patients with ischemic stroke using multi-algorithm machine learning and a nomogram.

Introduction: Ischemic stroke is a leading cause of mortality, and patients requiring intensive care unit (ICU) admission carry a guarded prognosis. W...

Apr 2 2026 41925182
CREsted: modeling genomic and synthetic cell-type-specific enhancers across tissues and species.

Sequence-based deep learning models have become the state of the art for analyzing the genomic regulatory code. Particularly for enhancers, these mode...

Apr 2 2026 41927920
LCPBert: ProtBERT-based early-stage lung cancer prediction from T cell receptor beta sequences.

Early detection of lung cancer remains challenging due to limitations of current methods. We developed LCPBert, a deep learning framework leveraging p...

Apr 1 2026 42023149
Artificial Intelligence-Based Exosome Analysis for Improving Diagnostic Performance of Breast Lesions on Ultrasound: Protocol of a Prospective, Multicenter Cohort Study.

PURPOSE: Exosome-surface enhanced Raman spectroscopy-artificial intelligence platform (exosome-SERS-AI) is an innovative liquid biopsy method that acq...

Apr 1 2026 41918185
mRNA vaccines in cancer immunotherapy: current progress and perspectives in solid tumors and hematologic malignancies.

The unprecedented success of mRNA vaccines during the COVID-19 pandemic has accelerated the development of nucleic acid-based therapeutics, particular...

Apr 1 2026 41920287
Re-evaluating heart rate variability biomarkers for glucose sensing: the impact of age normalisation and subject-independent validation.

BACKGROUND: Heart rate variability (HRV) derived from electrocardiogram (ECG) signals offers a promising non-invasive window into glycemic status; how...

Apr 1 2026 41923229
Machine Learning-assisted Prediction of Fluid Overload and Its Nursing Implications in Patients With Acute Pancreatitis.

Fluid overload (FO) is a critical complication in acute pancreatitis (AP), contributing to prolonged hospital stays and increased mortality. Tradition...

Apr 1 2026 41926460
Predictive Value of Machine Learning for Mortality Risk in Acute Pancreatitis: A Systematic Review and Meta-Analysis.

BACKGROUND: Acute pancreatitis (AP), a common acute abdominal disease, has a high mortality rate in severe cases. Accurate mortality prediction is cru...

Apr 1 2026 41397146
Fetal pHocus: A Novel Approach to Non-Invasive Fetal Arterial Blood pH Assessment via Near-Infrared Spectroscopy.

Modern intrapartum fetal health assessments are currently limited to monitoring heart rate and spatial parameters, neglecting critical biomarkers that...

Apr 1 2026 41852356
Assessment of the risk of bacteremia in patients with hematologic malignancies in the emergency department: A comparative study between logistic regression and machine learning algorithms.

OBJECTIVE: To stratify the risk of bacteremia at the time of emergency department (ED) admission in patients with hematologic malignancies. To this en...

Apr 1 2026 41880164
Retrieval-Augmented Language Models for Patient-Centered Periprocedural Anticoagulation in Interventional Radiology.

PURPOSE: This study evaluates Large Language Models (LLMs) integrated with Retrieval-Augmented Generation (RAG) frameworks for generating accurate, gu...

Apr 1 2026 41917168
Arrhythmias and cardiac devices management in oncology patients.

Cardiac arrhythmia is increasingly encountered in patients with cancer, not only as a result of shared risk factors but also as a direct consequence o...

Mar 31 2026 41933629
Dynamic machine learning prediction of persistent AKI after cardiac surgery with modifiable perioperative risk factors.

Early identification and prevention of persistent acute kidney injury (pAKI) remain challenging due to delayed biochemical markers and limited tools t...

Mar 31 2026 42058898
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