Hepatitis

Chronic kidney disease in Hepatitis C and its association with liver cirrhosis and viral load: Revealing the importance of hematuria.

Hepatitis C virus (HCV) contributed as a risk factor for chronic kidney disease (CKD). Many studies only showed it associated with estimated glomerular filtration rate (eGFR) reduction and albuminuria, but none revealed hematuria data. Besides, liver cirrhosis and viral load as risks for CKD are still yet to be established. This study aimed to assess the prevalence of CKD and its component in hepa...

Dermoscopic Features of Giant Molluscum Contagiosum in a Patient with Acquired Immunodeficiency Syndrome.

Giant molluscum contagiosum (MC) is a peculiar variant of the disease with the presence of multiple or single lesions larger than 5 mm. In contrast to typical molluscum contagiosum, dermoscopic features of giant lesions have been poorly described, and none of the reports included multiple giant lesions in an immunocompromised patient. We present a patient with acquired immunodeficiency syndrome di...

Development and validation of radiomics model built by incorporating machine learning for identifying liver fibrosis and early-stage cirrhosis.

BACKGROUND: Liver fibrosis (LF) continues to develop and eventually progresses to cirrhosis. However, LF and early-stage cirrhosis (ESC) can be revers...

Application of machine intelligence technology in the detection of vaccines and medicines for SARS-CoV-2.

Researchers have found many similarities between the 2003 severe acute respiratory syndrome (SARS) virus and SARS-CoV-19 through existing data that re...

Adapting and Extending a Typology to Identify Vaccine Misinformation on Twitter.

To adapt and extend an existing typology of vaccine misinformation to classify the major topics of discussion across the total vaccine discourse on T...

Study on the differentially expressed genes and signaling pathways in dermatomyositis using integrated bioinformatics method.

Dermatomyositis is a common connective tissue disease. The occurrence and development of dermatomyositis is a result of multiple factors, but its exac...

Assisting the Non-invasive Diagnosis of Liver Fibrosis Stages using Machine Learning Methods.

Fibrosis is a significant indication of chronic liver diseases often due to hepatitis C Virus. It is becoming a global concern as a result of the rapi...

A Bayesian classification model for discriminating common infectious diseases in Zhejiang province, China.

To develop a classification model for accurately discriminating common infectious diseases in Zhejiang province, China.Symptoms and signs, abnormal la...

Time series computational prediction of vaccines for influenza A H3N2 with recurrent neural networks.

Influenza viruses are persistently threatening public health, causing annual epidemics and sporadic pandemics due to rapid viral evolution. Vaccines a...

PathFlowAI: A High-Throughput Workflow for Preprocessing, Deep Learning and Interpretation in Digital Pathology.

The diagnosis of disease often requires analysis of a biopsy. Many diagnoses depend not only on the presence of certain features but on their location...

Multivariate Data Analysis and Machine Learning for Prediction of MCI-to-AD Conversion.

There has always been a need for discovering efficient and dependable Alzheimer's disease (AD) diagnostic biomarkers. Like the majority of diseases, t...

PVsiRNAPred: Prediction of plant exclusive virus-derived small interfering RNAs by deep convolutional neural network.

Plant exclusive virus-derived small interfering RNAs (vsiRNAs) regulate various biological processes, especially important in antiviral immunity. The ...

Relevant Features in Nonalcoholic Steatohepatitis Determined Using Machine Learning for Feature Selection.

We investigated the prevalence and the most relevant features of nonalcoholic steatohepatitis (NASH), a stage of nonalcoholic fatty liver disease, (N...

MRI-based prediction of conversion from clinically isolated syndrome to clinically definite multiple sclerosis using SVM and lesion geometry.

Neuroanatomical pattern classification using support vector machines (SVMs) has shown promising results in classifying Multiple Sclerosis (MS) patient...

Clinical Decision Support Systems: From the Perspective of Small and Imbalanced Data Set.

Clinical decision support systems are data analysis software that supports health professionals' decision - making the process to reach their ultimate...

Victors: a web-based knowledge base of virulence factors in human and animal pathogens.

Virulence factors (VFs) are molecules that allow microbial pathogens to overcome host defense mechanisms and cause disease in a host. It is critical t...

Safety and Immunogenicity of Two Doses of a Quadrivalent Meningococcal Polysaccharide Diphtheria Toxoid Conjugate Vaccine in Indian and Russian Children Aged 9 to 17 Months.

OBJECTIVE: Evaluation of tolerability, safety and immunogenicity of a two-dose series of a quadrivalent meningococcal polysaccharide diptheria toxoid ...

[A Case of Multiple Lung Metastases after Liver Resection for Multiple Hepatocellular Carcinomas with Remarkable Effects of Regorafenib].

The patient was a 63-year-old man with hepatitis C. He discontinued combination therapy containing interferon and ribavirin because of the development...

Serum Concentrations of Interferon Gamma (IFN-γ) in Patients with Psoriasis: Correlation with Clinical Type and Severity of the Disease.

INTRODUCTION: The etiopathogenesis of psoriasis is still unclear but there is evidence that many of cytokines released by keratinocytes and inflammato...

Three-dimensional direct laser writing of biomimetic neuron structures.

Building biomimetic neuron structures that emulate the topological features of biological neural networks at multiple scales has been an active area i...