Infectious Disease

HIV/AIDS

Latest AI and machine learning research in hiv/aids for healthcare professionals.

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Explainable machine learning framework for the molecular classification of triple negative breast cancer.

BACKGROUND AND OBJECTIVE: The difference in molecular characteristics of Triple negative breast cancer (TNBC) aids in distinguishing between its four prominent subtypes- basal-like 1, basal-like 2, mesenchymal, and luminal androgen receptor. This study presents the first integrative framework that combines explainable AI with machine learning approaches to classify TNBC subtypes. Unlike convention...

Feb 22 2026 41775141

A perturbed multilayer perceptron approach to predicting distant metastatic sites of cancer patients.

Cancer metastasis accounts for about 90% of cancer-related mortality, but is difficult to predict. In particular, distant metastasis is more difficult to predict by a learning method than lymph node metastasis due to the limited amount of data available for training a model and the inherent complexity of distant metastasis. Predicting distant metastatic sites from a primary cancer is even more dif...

Feb 20 2026 41723997
AID-FGS: Artificial intelligence-enabled diagnosis of female genital schistosomiasis: Preliminary findings.

Female genital schistosomiasis (FGS) is a sequela of infection with a waterborne parasite prevalent in sub-Saharan Africa and is associated with incre...

Feb 20 2026 41719365
Molecular interplay of ASNS and the PI3K-AKT-mTOR pathway in CMV and HIV co-infections: Therapeutic implications.

CMV/HIV coinfection markedly exacerbates disease progression, elevates treatment failure risk, and worsens patient outcomes, yet the underlying molecu...

Feb 20 2026 41719286
Enhancing LGBTQ+ Inclusivity in an AI-Powered Sexual Health Chatbot: User-Centered Design Approach Through a Nonprofit and Academic Partnership.

BACKGROUND: Despite the growing use of digital platforms for sexual health education, many tools fail to meet the needs of LGBTQ+ (lesbian, gay, bisex...

Feb 19 2026 41712769
Analysis of Associated Factors and Construction of Risk Prediction Models for Frailty in Hospitalized Older Adults Living With HIV: Protocol for a Prospective Observational Study.

BACKGROUND: The aging trend of people living with HIV or AIDS in China is increasing day by day. Frailty is a common condition among older adults livi...

Feb 19 2026 41712913
Artificial intelligence in orthopaedics: Enhanced examinations, ambient intelligence and the future of clinical practice.

Artificial intelligence (AI) continues to rapidly transform the practice of medicine, with clinicians increasingly adopting data-driven decision-makin...

Feb 18 2026 41705361
Identification of molecular diagnostic markers and potential therapeutic drugs for Sjögren's syndrome.

Sjögren's Syndrome (SS) is a long-term autoimmune disorder marked by damage to exocrine glands and irregularities in the immune system. Currently, the...

Feb 18 2026 41708714
Kaposi's sarcoma in individuals living with HIV: comparative assessment of AI-based clinical responses using a standardized questionnaire set.

OBJECTIVE: To comparatively evaluate the clinical responses of three digital platforms (ChatGPT 5.2, DeepSeek, Consensus) in terms of responsiveness, ...

Feb 15 2026 41693335
Benchmarking Generative AI Protein Models Reveals Differences Between Structural and Sequence-based Approaches.

Recent advances in artificial intelligence have led to the development of generative models for de novo protein design. We compared 13 state-of-the-ar...

Feb 15 2026 41693001
Peripheral immune landscape in pancreatic ductal adenocarcinoma reveals expansion of effector states with disease progression.

Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy often diagnosed late due to the limited sensitivity and specificity of current m...

Feb 14 2026 41797929
Identification and experimental confirmation of TBC1D10C as a shared transcriptional link between abdominal aortic aneurysm and major depressive disorder.

BACKGROUND: Abdominal aortic aneurysm (AAA) and major depressive disorder (MDD) are prevalent conditions with substantial global health burdens. Growi...

Feb 13 2026 41702190
Identification and validation of mitochondrial metabolism-ralated biomarkers in coronary heart disease.

Coronary heart disease (CHD) affects life quality of patients by impaired coronary artery blood supply. We were planning to study the molecular mechan...

Feb 13 2026 41686635
Overview of a User-Centered, Mixed-Methods Process for Designing Interconnected and Focused Mobile Applications on Patient Care Environment (InterFACE): Augmented-Reality Decision Support System for Pediatric Resuscitation.

BACKGROUND: Pediatric cardiopulmonary resuscitation (CPR) is a highly complex and time-critical process that demands precise team coordination and str...

Feb 13 2026 41687005
Temporal influence maximization via continuous-time graph neural networks and deep reinforcement learning.

Influence maximization (IM) seeks to identify a subset of key nodes that maximize the spread of information or behavior through a network. While tradi...

Feb 13 2026 41688564
Start4All protocol for a Bayesian cost-effectiveness model of tuberculosis screening and diagnosis in seven high burden low-income and middle-income countries.

INTRODUCTION: High costs of screening and diagnostic tests remain a major barrier to timely tuberculosis (TB) identification in resource-limited setti...

Feb 12 2026 41688116
Preoperative lymphocyte signature predicts pancreatic fistula after pancreatoduodenectomy.

BACKGROUND: Postoperative pancreatic fistula (POPF) is the major driver of postoperative morbidity after pancreatoduodenectomy (PD) and a healthcare i...

Feb 11 2026 41673079
Identification of mitochondrial dysfunction-related biomarkers and immune infiltration in liver ischemia-reperfusion injury via integrated bioinformatics and machine learning.

BACKGROUND: Mitochondrial dysfunction contributes to the pathogenesis of multiple diseases. This study explores the involvement of mitochondrial dysfu...

Feb 10 2026 41678948
High-Resolution MRI Using Artificial Intelligence-Assisted Acceleration and Radial Dynamic Contrast Enhancement for Improved Detection of Pituitary Microadenomas in Cushing's Disease.

BACKGROUND AND PURPOSE: Accurate detection of pituitary microadenomas is critical for the diagnosis and treatment of Cushing's disease (CD). However, ...

Feb 9 2026 41663207
Combating Antiviral Drug Resistance: A Multipronged Strategy.

ConspectusViral proteases are essential enzymes required for viral replication and assembly, making them prime antiviral drug targets. However, under ...

Feb 6 2026 41650319
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