Latest AI and machine learning research in inflammatory bowel disease for healthcare professionals.
Intestinal alkaline phosphatase (IAP) is a brush border enzyme critical for maintaining gut homeostasis by detoxifying bacterial endotoxins, regulating nutrient metabolism, and modulating immune responses. IAP activity is modulated by dietary components such as carbohydrates, fats, probiotics, and vitamins, and has a dose-dependent effect. It strengthens intestinal barrier function by upregulating...
The present manuscript provides a comprehensive overview of neural stem cell (NSC)-derived extracellular vesicles (NSC-EVs( as a cell-free approach to treating central nervous system (CNS) disorders. The study noted that NSCs are regenerative and neuroprotective, but direct transplantation is limited by short survival, immunological rejection, and tumorigenic risk. However, NSC-EVs-nano-sized vesi...
Steroid-induced osteonecrosis of the femoral head (SONFH) is a major cause of disability among young and middle-aged adults. However, current diagnosi...
BACKGROUND: Colorectal cancer is a major global health burden, with most cases arising from adenomatous polyps. Although colonoscopy is the gold stand...
BACKGROUND: Precision theranostics in nuclear medicine requires reproducible, calibrated quantification of tissue perfusion, and metabolism. This stud...
BACKGROUND: Ulcerative colitis (UC) exhibits substantial heterogeneity in inflammatory pathways and therapeutic response. The organic cation transport...
BACKGROUND: Emerging evidence implicates eosinophils as important modulators of disease activity and therapeutic response in ulcerative colitis. Autom...
Mycobacterial pathogens remain major global health threats, exacerbated by both rapid acquisition of antibiotic resistance and the formidable drug dif...
Inflammatory bowel disease (IBD) is a chronic condition driven by the intertwined interplay of gut dysbiosis, immune perturbation, and metabolic imbal...
BACKGROUND: The potential multidimensional molecular alterations during recovery of severe patients with coronavirus infectious disease (COVID-19) rem...
Lynch syndrome (LS) is the most common hereditary colorectal cancer (CRC) syndrome and is characterized by an accelerated adenoma-carcinoma sequence, ...
Type 2 diabetes (T2D), inflammatory bowel disease (IBD), and colorectal cancer (CRC) share overlapping metabolic alterations that hinder early, diseas...
Inflammatory bowel disease (IBD) is frequently accompanied by intestinal fibrosis, with non-response (NR) to long-term anti-tumor necrosis factor α (a...
Looping during colonoscopy procedures is a major cause of patient discomfort and increases the risk of complications. With the rising incidence of col...
INTRODUCTION: Adrenocortical tumors (ACTs) comprise adrenocortical adenomas (ACAs) and adrenocortical carcinomas (ACCs); the latter are highly aggress...
Graves' disease (GD) is an autoimmune entity that had an unchanged treatment paradigm for more than half a century with radioactive iodine, antithyroi...
The integration of measurable residual disease (MRD) into the management of chronic lymphocytic leukemia (CLL) has emerged as a major advance in risk ...
BACKGROUND: Chronic pancreatitis (CP) is a progressive inflammatory disorder characterized by debilitating chronic pain and substantial healthcare bur...
Biologics is emerging as fastest growing field of drug development offering specificity and high therapeutic potential. However, their therapeutic eff...