Lung Cancer

Integrating artificial intelligence with endoscopic ultrasound in the early detection of bilio-pancreatic lesions: Current advances and future prospects.

The integration of Artificial Intelligence (AI) in endoscopic ultrasound (EUS) represents a transformative advancement in the early detection and management of biliopancreatic lesions. This review highlights the current state of AI-enhanced EUS (AI-EUS) for diagnosing solid and cystic pancreatic lesions, as well as biliary diseases. AI-driven models, including machine learning (ML) and deep learni...

Explainable Machine Learning to Predict Treatment Response in Advanced Non-Small Cell Lung Cancer.

PURPOSE: Immune checkpoint inhibitors (ICIs) have demonstrated promise in the treatment of various cancers. Single-drug ICI therapy (immuno-oncology [IO] monotherapy) that targets PD-L1 is the standard of care in patients with advanced non-small cell lung cancer (NSCLC) with PD-L1 expression ≥50%. We sought to find out if a machine learning (ML) algorithm can perform better as a predictive biomark...

A GPU-accelerated fuzzy method for real-time CT volume filtering.

During acquisition and reconstruction, medical images may become noisy and lose diagnostic quality. In the case of CT scans, obtaining less noisy imag...

Identification of key gene signatures for predicting chemo-immunotherapy efficacy in extensive-stage small-cell lung cancer using machine learning.

OBJECTIVES: The lack of definitive biomarkers presents a significant challenge for chemo-immunotherapy in extensive-stage small-cell lung cancer (ES-S...

Exploring machine learning tools in a retrospective case-study of patients with metastatic non-small cell lung cancer treated with first-line immunotherapy: A feasibility single-centre experience.

BACKGROUND: Artificial intelligence (AI) models are emerging as promising tools to identify predictive features among data coming from health records....

Identification of Factors Influencing Donor-Derived Cell-Free DNA Levels up to One Year After Kidney Transplant.

Donor-derived cell-free DNA (dd-cfDNA) in the peripheral blood of allograft recipients has shown to early identify allograft injury. In this study, w...

AI-Driven insights in pancreatic cancer imaging: from pre-diagnostic detection to prognostication.

Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer-related deaths in the United States, largely due to its poor five-year su...

Analysis of diagnostic genes and molecular mechanisms of Crohn's disease and colon cancer based on machine learning algorithms.

Crohn's disease (CD) is a chronic inflammatory bowel condition, and colon adenocarcinoma (COAD), as one of the most prevalent malignant tumors of the ...

Radiomics for differentiating adenocarcinoma and squamous cell carcinoma in non-small cell lung cancer beyond nodule morphology in chest CT.

Distinguishing between primary adenocarcinoma (AC) and squamous cell carcinoma (SCC) within non-small cell lung cancer (NSCLC) tumours holds significa...

Assessing the value of deep neural networks for postoperative complication prediction in pancreaticoduodenectomy patients.

INTRODUCTION: Pancreaticoduodenectomy (PD) for patients with pancreatic ductal adenocarcinoma (PDAC) is associated with a high risk of postoperative c...

Multimodal Deep Learning Fusing Clinical and Radiomics Scores for Prediction of Early-Stage Lung Adenocarcinoma Lymph Node Metastasis.

RATIONALE AND OBJECTIVES: To develop and validate a multimodal deep learning (DL) model based on computed tomography (CT) images and clinical knowledg...

Comparative investigation of lung adenocarcinoma and squamous cell carcinoma transcriptome to reveal potential candidate biomarkers: An explainable AI approach.

Patients with Non-Small Cell Lung Cancer (NSCLC) present a variety of clinical symptoms, such as dyspnea and chest pain, complicating accurate diagnos...

Development and external validation of a multi-task feature fusion network for CTV segmentation in cervical cancer radiotherapy.

BACKGROUND AND PURPOSE: Accurate segmentation of the clinical target volume (CTV) is essential to deliver an effective radiation dose to tumor tissues...

Descriptive overview of AI applications in x-ray imaging and radiotherapy.

Artificial intelligence (AI) is transforming medical radiation applications by handling complex data, learning patterns, and making accurate predictio...

Accuracy of machine learning models for pre-diagnosis and diagnosis of pancreatic ductal adenocarcinoma in contrast-CT images: a systematic review and meta-analysis.

PURPOSE: To evaluate the diagnostic ability and methodological quality of ML models in detecting Pancreatic Ductal Adenocarcinoma (PDAC) in Contrast C...

A unified deep-learning framework for enhanced patient-specific quality assurance of intensity-modulated radiation therapy plans.

BACKGROUND: Modern radiation therapy techniques, such as intensity-modulated radiation therapy (IMRT) and volumetric-modulated arc therapy (VMAT), use...

Automated treatment planning with deep reinforcement learning for head-and-neck (HN) cancer intensity modulated radiation therapy (IMRT).

To develop a deep reinforcement learning (DRL) agent to self-interact with the treatment planning system to automatically generate intensity modulated...

Automated Measurement of Effective Radiation Dose by F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography.

BACKGROUND/OBJECTIVES: Calculating the radiation dose from CT in F-PET/CT examinations poses a significant challenge. The objective of this study is t...

Artificial intelligence in lung cancer: current applications, future perspectives, and challenges.

Artificial intelligence (AI) has significantly impacted various fields, including oncology. This comprehensive review examines the current application...

Improving prediction of solar radiation using Cheetah Optimizer and Random Forest.

In the contemporary context of a burgeoning energy crisis, the accurate and dependable prediction of Solar Radiation (SR) has emerged as an indispensa...