Latest AI and machine learning research in lupus for healthcare professionals.
Persistent infection with high-risk types Human Papillomavirus could cause diseases including cervical cancers and oropharyngeal cancers. Nonetheless, so far there is no effective pharmacotherapy for treating the infection from high-risk HPV types, and hence it remains to be a severe threat to the health of female. Based on drug repositioning strategy, we trained and benchmarked multiple machine l...
Apoptosis plays an essential role in maintaining cellular homeostasis and preventing cancer progression. Bcl-xL, an anti-apoptotic protein, is an important modulator of the mitochondrial apoptosis pathway and is a promising target for anticancer therapy. In this study, we identified octenidine as a novel Bcl-xL inhibitor through structural feature-based deep learning and molecular docking from a l...
Therapies halting the progression of fibrosis are ineffective and limited. Activated myofibroblasts are emerging as important targets in the progressi...
: The lumbar stabilization exercise is one of the most recommended treatments in medical professionals for patients suffering from low back pain. Howe...
Boesenbergia pandurata and its major active ingredient, panduratin A (PAN), exhibit antibacterial, anti-oxidant, anti-inflammatory, and anti-obesity e...
Anti-tuberculosis fixed-dose combinatorial formulation (FDCs) is an effective drug for the treatment of tuberculosis. As a compound medicine, its effi...
The spread of different types of cancer has been on a rise in the recent century. The use of chemical medications develops drug resistance and causes ...
Kynurenine (Kyn) is a key inducer of an immunosuppressive tumor microenvironment (TME). Although indoleamine 2,3-dioxygenase (IDO)-selective inhibitor...
OBJECTIVE: The aim of this study was to evaluate the feasibility of machine learning approach based on clinical factors and diffusion tensor imaging (...
BACKGROUND: Few models to predict antiviral response of peginterferon were used in hepatitis B e antigen (HBeAg)-positive chronic hepatitis B patients...
No anti-cocaine addiction drugs have been approved by the Food and Drug Administration despite decades of effort. The main challenge is the intricate ...
The aim of this study was to evaluate the antioxidant and anti-proliferative activity of different fractions of phenolic compounds from tomato and tom...
The theoretical prediction of drug-decorated nanoparticles (DDNPs) has become a very important task in medical applications. For the current paper, Pe...
S4A ((1,2,3)-1,2-propanediol acetal-zeylenone) is one of the derivatives of zeylenone and exhibits superior cytotoxicity against the canine breast can...
Various intelligent technologies have been applied during COVID-19, which has become a worldwide public health emergency and brought significant chall...
Banks and financial institutions are vulnerable to money laundering (ML) as a result of crime proceeds infiltrating banks in the form of significant ...
Cancer immunotherapy provides durable clinical benefit in only a small fraction of patients, and identifying these patients is difficult due to a lack...
The diversification of the characteristic sequences of anti-cancer peptides has imposed difficulties on research. To effectively predict new anti-canc...
Anti-inflammatory peptides (AIEs) have recently emerged as promising therapeutic agent for treatment of various inflammatory diseases, such as rheumat...
Leishmaniasis is a disease that represents a serious global health problem with a potentially fatal outcome in some cases. spp. is transmitted by the...