Cardiovascular

Metabolic Syndrome

Latest AI and machine learning research in metabolic syndrome for healthcare professionals.

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Moderate, Short-Term, Local Hyperglycemia Attenuates Forearm Endothelium-Dependent Vasodilation After Transient Ischemia-Reperfusion in Human Volunteers.

OBJECTIVE: Acute hyperglycemia causes endothelial dysfunction in diabetic patients, abolishes ischemic pre- and postconditioning, and is an independent predictor of adverse outcome after myocardial infarction in nondiabetic patients. Its effects on endothelial-dependent vasodilation are controversial in healthy subjects. The authors studied the effect of moderate short-term local hyperglycemia on ...

Dec 2 2016 28284926

Dyslipidemia and its relationship with antiphospholipid antibodies in APS patients in North Kerala.

OBJECTIVE: Antiphospholipid antibody syndrome (APS) is one of the most common acquired thrombophilic disorders resulting in arterial and venous thromboses. APS is a major cause for cerebrovascular accidents or stokes, myocardial infarction, venous thromboembolism and recurrent abortions/pregnancy losses especially in young patients. APS patients have an increased risk of atherosclerotic cardiovasc...

Dec 1 2016 28149659
Impact of vitamin D status on statin-induced myopathy.

INTRODUCTION: There is a multitude of evidence supporting the benefit of statin use in cardiovascular disease; however, statin-induced myopathy is a m...

Nov 23 2016 29067242
Integration of metabolomics, lipidomics and clinical data using a machine learning method.

BACKGROUND: The recent pandemic of obesity and the metabolic syndrome (MetS) has led to the realisation that new drug targets are needed to either red...

Nov 22 2016 28185575
Physiological study on the influence of some plant oils in rats exposed to a sublethal concentration of diazinon.

The present study was aimed to evaluate the influence of olive, sesame and black seed oils on levels of some physiological parameters in male rats exp...

Nov 10 2016 29740245
Effects of Dietary Approach to Stop Hypertension diet on androgens, antioxidant status and body composition in overweight and obese women with polycystic ovary syndrome: a randomised controlled trial.

BACKGROUND: Polycystic ovary syndrome (PCOS) is the most common endocrine disease in reproductive age women. The present study aimed to determine the ...

Nov 7 2016 28466507
High Molecular Weight Adiponectin Levels are Neither Influenced by Adiponectin Polymorphisms Nor Associated with Insulin Resistance in Mixed-ancestry Hyperglycemic Subjects from South Africa.

BACKGROUND: High molecular weight (HMW) adiponectin has antiatherogenic, antiinflammatory and antidiabetic properties and these effects have been link...

Nov 2 2016 28670194
Vitamin D status, hypertension and body mass index in an urban black community in Mangaung, South Africa.

BACKGROUND: A strong relationship exists between hypertension and body weight. Research has linked both higher blood pressure and body weight with low...

Oct 31 2016 28155313
The Pre-Eclampsia Ontology: A Disease Ontology Representing the Domain Knowledge Specific to Pre-Eclampsia.

Pre-eclampsia (PE) is a clinical syndrome characterized by new-onset hypertension and proteinuria at ≥20 weeks of gestation, and is a leading cause of...

Oct 27 2016 27788142
Food Insecurity among American Indians and Alaska Natives: A National Profile using the Current Population Survey-Food Security Supplement.

Food insecurity increases the risk for obesity, diabetes, hypertension, and cancer-conditions highly prevalent among American Indians and Alaska Nativ...

Oct 25 2016 28491205
Resistant starch suppresses postprandial hypertriglyceridemia in rats.

Postprandial increase in blood triglyceride levels is an independent risk factor for coronary artery disease, and dietary resistant starch (RS) is inc...

Oct 15 2016 28460986
Adaptations to excess choline in insulin resistant and Pcyt2 deficient skeletal muscle.

It was hypothesized that choline supplementation in insulin resistant (IR) CTP:phosphoethanolamine cytidylyltransferase deficient (Pcyt2) mice would a...

Sep 6 2016 28068143
inhibits the absorption and synthesis of cholesterol .

BACKGROUND: (SN) has many nutritional benefits and it is commonly used to ameliorate different human conditions including inflammation, gastric ulcer...

Aug 22 2016 28462132
Correlation of compliance to statin therapy with lipid profile and serum HMGCoA reductase levels in dyslipidemic patients.

BACKGROUND: The efficacy of statin therapy may be lost or vary with reduction in compliance and intensity of statin therapy.

Aug 1 2016 28228309
Diet-induced weight loss and markers of endothelial dysfunction and inflammation in treated patients with type 2 diabetes.

BACKGROUND & AIMS: Overweight and obesity increase cardiovascular mortality in patients with type 2 diabetes (T2D). In a recent trial, however, diet-i...

Jul 25 2016 28531772
Compounding and stability evaluation of atorvastatin extemporaneous oral suspension using tablets or pure powder.

BACKGROUND: Statins are the first-line therapy for lowering high lipid levels. Atorvastatin calcium (AtC) is the most commonly prescribed statin. It i...

Jun 15 2016 31156928
Serum Lipid Alterations in Early Rheumatoid Arthritis Patients on Disease Modifying Anti Rheumatoid Therapy.

Dyslipidaemia is a major CVD risk factor in the general population. Current evidence suggests that lipid metabolism is altered in RA due to inflammati...

Apr 22 2016 28149009
Dietary triglycerides as signaling molecules that influence reward and motivation.

The reinforcing and motivational aspects of food are tied to the release of the dopamine in the mesolimbic system (ML). Free fatty acids from triglyce...

Mar 18 2016 28191490
Postural Changes in Measures of Arterial Stiffness in Hypertensive Subjects on Antihypertensive Drug Therapy: A Prospective, Pilot Study.

Prospective study with a controlled arm to know if there are variations of measures of arterial stiffness with posture in subjects with hypertension o...

Feb 4 2016 28566932
Structural Insights into High Density Lipoprotein: Old Models and New Facts.

The physiological link between circulating high density lipoprotein (HDL) levels and cardiovascular disease is well-documented, albeit its intricacies...

Jan 12 2016 26793109
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