Nephrology

Latest AI and machine learning research in nephrology for healthcare professionals.

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Machine learning-derived clinical phenotypes of ascites in cirrhosis: A multi-center latent class analysis with external validation.

BACKGROUND: Ascites development in cirrhosis reduces five-year survival from 80% to 30%, yet substantial heterogeneity exists among patients with comparable ascites severity. METHODS: This multicenter retrospective cohort study included adult liver transplant candidates with ascites at four United States centers (2015-2024). Latent class analysis was performed using seven clinical variables: ascit...

Aug 6 2026 42560069

Prediction of Incident Atrial Fibrillation and Association With Outcomes Using Routine Electronic Health Records in a Western Pacific Population.

BACKGROUND AND AIM: Atrial fibrillation (AF) affects over 37 million people internationally and confers increased risk of cardiovascular conditions. Prediction algorithms have attempted to predict incident AF, but other cardio-renal diseases could also provide targets for earlier intervention. METHOD: We derived a random forest classified for incident AF within 5 years (Future Innovations in Novel...

Aug 6 2026 42562672
A study on risk factors for the progression from T2DM to end-stage renal disease based on Mendelian randomization and logistic regression analysis.

Using two-sample Mendelian randomization (MR) based on GWAS data from the IEU OpenGWAS project and a retrospective clinical cohort, this study investi...

Aug 5 2026 42556871
Machine Learning Classification of Prevalent Chronic Disease Using Multidimensional Social, Behavioral, and Psychological Determinants: A Cross-Sectional Analysis of the 2024 National Health Interview Survey.

BACKGROUND: Chronic diseases account for approximately 90% of the $4.5 trillion annual healthcare expenditure in the United States. While traditional ...

Aug 5 2026 42556439
GERBEHRT: a BERT-based model tailored for German electronic health records - potential in chronic kidney disease prediction.

BACKGROUND: Chronic kidney disease (CKD) is a critical, progressive condition associated with high mortality and substantial healthcare costs. Early d...

Aug 5 2026 42557565
Identification of intradialytic hemodynamic phenotypes using latent profile analysis.

BACKGROUND: Intradialytic blood pressure variations are frequent and associated with poor clinical outcomes. However, the use of arbitrary, inconsiste...

Aug 4 2026 42682856
Beyond the guidelines: Vascular function as the central determinant and therapeutic target in hypertension.

Hypertension has traditionally been defined and managed according to brachial blood pressure levels. Although this pressure-centric strategy has signi...

Aug 4 2026 42552401
Artificial intelligence empowers full-stack histopathological diagnosis and prognosis of renal cell tumor: a multi-center study with external validation.

BACKGROUND: The rapid advancement of digital pathology has opened unprecedented opportunities for intelligent diagnosis in renal cell tumor. However, ...

Aug 4 2026 42547870
The FERM guild: a differentially correlated microbial module drives hypertension via metabolic flux perturbations.

UNLABELLED: Hypertension is a major risk factor for cardiovascular diseases, with changes in gut microbiota composition and function being closely ass...

Aug 4 2026 42549911
Plasma proteomics linking primary and secondary diseases: Insights into molecular mediation from UK Biobank data.

BACKGROUND: Diabetes, hypertension, and dyslipidemia are major risk factors for cardiovascular, neurological, renal, and pulmonary diseases, yet clini...

Aug 4 2026 42551443
Serum Receptor-Interacting Protein Kinase 3 (RIPK3) Is Associated with Transplant-Free Survival in Acute Liver Failure.

BACKGROUND AND AIMS: Prognostication in acute liver failure (ALF) due to acetaminophen (APAP) and other causes of drug-induced liver injury (DILI) rem...

Aug 4 2026 42551529
Nonoperating room anesthesia in the ICU: current practice and considerations.

PURPOSE OF REVIEW: ICU procedures are increasingly complex, often requiring deeper sedation or general anesthesia, and are increasingly performed at t...

Aug 4 2026 42546269
Machine Learning Approaches to Identify Influential Factors of the Comorbid Psychiatric Symptoms and Hypertension Among Rural Adults in Bangladesh: A Cross-Sectional Study.

BACKGROUND AND AIM: The burden of both psychiatric symptoms (anxiety and/or depression) and hypertension poses significant public health challenges in...

Aug 4 2026 42553476
A machine learning-based framework for predicting type 2 diabetes mellitus using hematological indices.

OBJECTIVE: This study aimed to develop a machine learning (ML) framework to predict incident type 2 diabetes mellitus (T2DM) using routinely available...

Aug 3 2026 42602976
Kidney-specific deletion of the BicC family RNA-binding protein 1 triggers an ADPKD-like cystogenic program.

Autosomal dominant polycystic kidney disease (ADPKD) arises from mutations in polycystin-1/PKD1 or polycystin-2/PKD2 that induce injury-repair pathway...

Aug 3 2026 42597841
Comparison of Machine Learning and Logistic Regression in Predicting Mortality from Acute Poisoning in Young Adults: A Multicenter Study Identifying Herbicide Exposure as the Predominant Risk Determinant.

OBJECTIVE: Compare the effectiveness of machine learning algorithms and traditional logistic regression in predicting the mortality risk of young pati...

Aug 3 2026 42545042
Prognostication in Autosomal Dominant Polycystic Kidney Disease: Current Tools, Clinical Gaps, and Future Directions.

Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most prevalent hereditary kidney disorder. While the disease is well-defined, its clinical...

Aug 3 2026 42545852
Deep learning-supported image quantification of epithelial cell shapes and its application to polycystic kidney disease.

Cell shape is a fundamental determinant of tissue architecture and organ function. In epithelial tissues, cytoskeletal organization and apical junctio...

Aug 3 2026 42546061
Clinical and Echocardiographic Factors Associated With AI-Estimated Atrial Fibrillation Likelihood During Sinus Rhythm in Patients With Documented Paroxysmal Atrial Fibrillation.

BACKGROUND: Artificial intelligence-enabled electrocardiography (AI-ECG) has emerged as a promising tool for identifying patients with atrial fibrilla...

Aug 3 2026 42549027
Real-Time Anatomy Recognition During Single-Port Retroperitoneal Surgery: A Prospective Comparison Between AI and Operating Surgeon.

BACKGROUND: Real-time anatomical recognition during robot-assisted surgery has the potential to enrich intraoperative decision-making. We made the fir...

Aug 1 2026 42541387
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