Oncology/Hematology

Latest AI and machine learning research in oncology/hematology for healthcare professionals.

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Showing 15241-15260 of 19,075 articles

A Conformal Prediction Approach to Enhance Predictive Accuracy and Confidence in Machine Learning Application in Chronic Diseases.

Heterogeneity in chronic malignancies raises an increasing interest for the integration and study of predictive models. This study presents a machine learning model approach to predict outcomes and improve their trustworthiness in multi-factorial diseases with highly heterogeneous outcomes, like Chronic Lymphocytic Leukemia (CLL). We incorporated Conformal Prediction to quantify our models uncerta...

Aug 22 2024 39176913

Using Retrieval-Augmented Generation to Capture Molecularly-Driven Treatment Relationships for Precision Oncology.

Modern generative artificial intelligence techniques like retrieval-augmented generation (RAG) may be applied in support of precision oncology treatment discussions. Experts routinely review published literature for evidence and recommendations of treatments in a labor-intensive process. A RAG pipeline may help reduce this effort by providing chunks of text from these publications to an off-the-sh...

Aug 22 2024 39176956
Bioimpedance a Diagnostic Tool for Tobacco Induced Oral Lesions: a Mixed Model cross-sectional study

Introduction: Electrical impedance spectroscopy (EIS) has recently developed as a novel diagnostic device for screening and evaluating cervical dysp...

ST-USleepNet: A Spatial-Temporal Coupling Prominence Network for Multi-Channel Sleep Staging

Sleep staging is critical to assess sleep quality and diagnose disorders. Despite advancements in artificial intelligence enabling automated sleep s...

Screen Them All: High-Throughput Pan-Cancer Genetic and Phenotypic Biomarker Screening from H&E Whole Slide Images

Many molecular alterations serve as clinically prognostic or therapy-predictive biomarkers, typically detected using single or multi-gene molecular ...

Personalized graph feature-based multi-omics data integration for cancer subtype identification

Cancer is a highly heterogeneous disease with significant variability in molecular features and clinical outcomes, making diagnosis and treatment ch...

Assessment of readability, reliability, and quality of ChatGPT®, BARD®, Gemini®, Copilot®, Perplexity® responses on palliative care.

There is no study that comprehensively evaluates data on the readability and quality of "palliative care" information provided by artificial intellige...

Aug 16 2024 39151545
Novel Methods for Analyzing Cellular Interactions in Deep Learning-Based Image Cytometry: Spatial Interaction Potential and Co-Localization Index

The study presents a novel approach for quantifying cellular interactions in digital pathology using deep learning-based image cytometry. Traditiona...

Deep Learning: a Heuristic Three-stage Mechanism for Grid Searches to Optimize the Future Risk Prediction of Breast Cancer Metastasis Using EHR-based Clinical Data

A grid search, at the cost of training and testing a large number of models, is an effective way to optimize the prediction performance of deep lear...

Pan-cancer gene set discovery via scRNA-seq for optimal deep learning based downstream tasks

The application of machine learning to transcriptomics data has led to significant advances in cancer research. However, the high dimensionality and...

Multimodal Analysis of White Blood Cell Differentiation in Acute Myeloid Leukemia Patients using a β-Variational Autoencoder

Biomedical imaging and RNA sequencing with single-cell resolution improves our understanding of white blood cell diseases like leukemia. By combinin...

Machine learning enables pan-cancer identification of mutational hotspots at persistent CTCF binding sites.

CCCTC-binding factor (CTCF) is an insulator protein that binds to a highly conserved DNA motif and facilitates regulation of three-dimensional (3D) nu...

Aug 12 2024 38950902
Advancements in Programmable Lipid Nanoparticles: Exploring the Four-Domain Model for Targeted Drug Delivery

Programmable lipid nanoparticles, or LNPs, represent a breakthrough in the realm of targeted drug delivery, offering precise spatiotemporal control ...

Advancing oncology with federated learning: transcending boundaries in breast, lung, and prostate cancer. A systematic review

Federated Learning (FL) has emerged as a promising solution to address the limitations of centralised machine learning (ML) in oncology, particularl...

An Integral R-Banded Karyotype Analysis System of Bone Marrow Metaphases Based on Deep Learning.

CONTEXT.—: Conventional karyotype analysis, which provides comprehensive cytogenetic information, plays a significant role in the diagnosis and risk s...

Aug 1 2024 37931220
Combined bioinformatics and machine learning methodologies reveal prognosis-related ceRNA network and propose ABCA8, CAT, and CXCL12 as independent protective factors against osteosarcoma.

BACKGROUND: Aberrant circular RNA (circRNA) acts as an oncogene or suppressor during neoplasm initiation and development. However, the functions of mo...

Aug 1 2024 38315381
Identification of effective diagnostic genes and immune cell infiltration characteristics in small cell lung cancer by integrating bioinformatics analysis and machine learning algorithms.

OBJECTIVES: To identify potential diagnostic markers for small cell lung cancer (SCLC) and investigate the correlation with immune cell infiltration.

Aug 1 2024 39074893
Integrating single-cell transcriptomics and machine learning to predict breast cancer prognosis: A study based on natural killer cell-related genes.

Breast cancer (BC) is the most commonly diagnosed cancer in women globally. Natural killer (NK) cells play a vital role in tumour immunosurveillance. ...

Aug 1 2024 39098994
Machine learning and deep learning tools for the automated capture of cancer surveillance data.

The National Cancer Institute and the Department of Energy strategic partnership applies advanced computing and predictive machine learning and deep l...

Aug 1 2024 39102883
Fully Automated Deep Learning Model to Detect Clinically Significant Prostate Cancer at MRI.

Background Multiparametric MRI can help identify clinically significant prostate cancer (csPCa) (Gleason score ≥7) but is limited by reader experience...

Aug 1 2024 39105640
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