Peptic Ulcer Disease

Protein Complexes Detection Based on Semi-Supervised Network Embedding Model.

A protein complex is a group of associated polypeptide chains which plays essential roles in the biological process. Given a graph representing protein-protein interactions (PPI) network, it is critical but non-trivial to detect protein complexes, the subsets of proteins that are tightly coupled, from it. Network embedding is a technique to learn low-dimensional representations of vertices in netw...

Comparison of plasma neutrophil gelatinase-associated lipocalin (NGAL) levels after robot-assisted laparoscopic and retropubic radical prostatectomy: an observational study.

BACKGROUND AND OBJECTIVES: Patients undergoing radical prostatectomy are at increased risk of Acute Kidney Injury (AKI) because of intraoperative bleeding, obstructive uropathy, and older age. Neutrophil Gelatinase-Associated Lipocalin (NGAL) may become important for diagnosis of postoperative AKI after urogenital oncosurgery. The objective of this study was to evaluate and compare the efficacy of...

Identification of novel inhibitors of Keap1/Nrf2 by a promising method combining protein-protein interaction-oriented library and machine learning.

Protein-protein interactions (PPIs) are prospective but challenging targets for drug discovery, because screening using traditional small-molecule lib...

IL-8, MSPa, MIF, FGF-9, ANG-2 and AgRP collection were identified for the diagnosis of colorectal cancer based on the support vector machine model.

Colorectal cancer (CRC) is one of the most common cancer, and the early detection of CRC is essential to improve the survival rate of patients. To ide...

Robotic infant surgery with 3 mm instruments: a study in piglets of less than 10 kg body weight.

No data exist concerning the appication of a new robotic system with 3 mm instruments (Senhance®, Transenterix) in infants and small children. Therefo...

Management of Significant Airway Bleeding during Robotic Assisted Bronchoscopy: A Tailored Approach.

Robotic assisted bronchoscopy represents a major turning point in bronchoscopic history. The management strategies to address significant airway bleed...

Small Bowel Capsule Endoscopy and artificial intelligence: First or second reader?

Several machine learning algorithms have been developed in the past years with the aim to improve SBCE (Small Bowel Capsule Endoscopy) feasibility ens...

Using deep learning to predict temporomandibular joint disc perforation based on magnetic resonance imaging.

The goal of this study was to develop a deep learning-based algorithm to predict temporomandibular joint (TMJ) disc perforation based on the findings ...

Deep Transfer Learning for Automated Intestinal Bleeding Detection in Capsule Endoscopy Imaging.

PURPOSE: The objective of this paper was to develop a computer-aided diagnostic (CAD) tools for automated analysis of capsule endoscopic (CE) images, ...

The evolving role of EUS-guided tissue acquisition.

The introduction of endoscopic ultrasound-guided fine-needle aspiration into clinical practice was a pivotal moment for diagnostic gastrointestinal en...

The effect of diabetes on major robotic hepatectomy.

Studies regarding the influence of diabetes on perioperative outcomes after major hepatectomy are conflicting. The objective of this study is to analy...

Recapitulating the Binding Affinity of Nrf2 for KEAP1 in a Cyclic Heptapeptide, Guided by NMR, X-ray Crystallography, and Machine Learning.

Macrocycles, including macrocyclic peptides, have shown promise for targeting challenging protein-protein interactions (PPIs). One PPI of high interes...

A Deep Learning Model for Classification of Endoscopic Gastroesophageal Reflux Disease.

Gastroesophageal reflux disease (GERD) is a common disease with high prevalence, and its endoscopic severity can be evaluated using the Los Angeles cl...

An inguinal hernia that arose after robot-assisted radical prostatectomy and the repair of an intraoperative external iliac vein injury: A case report.

This case involved a 63-year-old man. He underwent robot-assisted radical prostatectomy (RARP) for prostate cancer. One year after the operation, he c...

Colorectal polyp characterization with standard endoscopy: Will Artificial Intelligence succeed where human eyes failed?

The American Society for Gastrointestinal Endoscopy (ASGE) has proposed the "resect-and-discard" and "diagnose-and-leave" strategies for diminutive co...

Deep learning for detection and segmentation of artefact and disease instances in gastrointestinal endoscopy.

The Endoscopy Computer Vision Challenge (EndoCV) is a crowd-sourcing initiative to address eminent problems in developing reliable computer aided dete...

VR-Caps: A Virtual Environment for Capsule Endoscopy.

Current capsule endoscopes and next-generation robotic capsules for diagnosis and treatment of gastrointestinal diseases are complex cyber-physical pl...

Multi-Scale Context-Guided Deep Network for Automated Lesion Segmentation With Endoscopy Images of Gastrointestinal Tract.

Accurate lesion segmentation based on endoscopy images is a fundamental task for the automated diagnosis of gastrointestinal tract (GI Tract) diseases...

A Deep Learning Framework for Identifying Essential Proteins by Integrating Multiple Types of Biological Information.

Computational methods including centrality and machine learning-based methods have been proposed to identify essential proteins for understanding the ...

Protein2Vec: Aligning Multiple PPI Networks with Representation Learning.

Research of Protein-Protein Interaction (PPI) Network Alignment is playing an important role in understanding the crucial underlying biological knowle...