Primary Care

Latest AI and machine learning research in primary care for healthcare professionals.

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Validation of a pan-ELastography Machine-learning (ELM) score to predict clinically significant portal hypertension in compensated advanced chronic liver disease.

BACKGROUND: Clinically significant portal hypertension (CSPH) drives decompensation and mortality in advanced chronic liver disease (ACLD). Although non-selective β-blockers (NSBB) reduce risk, accurate identification of patients with CSPH requires invasive hepatic venous pressure gradient (HVPG) measurement. The non-invasive Baveno-VII CSPH criteria based on liver stiffness measurement (LSM) and ...

Jul 8 2026 42419604

Evaluating the role of youth-onset diabetes mellitus in the context of food insecurity and preventive care: a repeated cross-sectional study using propensity score weighted machine learning analysis.

BACKGROUND: Youth-onset diabetes mellitus (DM) is an increasing public health concern, especially among adolescents facing socioeconomic challenges. Food insecurity (FI), a key social determinant of health, has been linked to adverse metabolic outcomes, but its association with youth-onset DM and the role of preventive care remain unclear. METHODS: Using repeated cross-sectional data from the Nati...

Jul 8 2026 42419911
Development of a target product profile for artificial intelligence in diabetic eye screening in England: a modified Delphi consensus study.

Artificial intelligence (AI) health-care technologies offer a means of addressing the growing gap between health-care capacity and demand. However, fe...

Jul 8 2026 42420060
An optimized ensemble learning model for interpretable and efficient obesity classification.

Obesity is a major health challenge resulting from the interaction of genetic, behavioral, and environmental factors. In recent years, several convent...

Jul 8 2026 42414448
Risk prediction for lung cancer screening: a systematic review and meta-regression.

BACKGROUND: Lung cancer (LC) remains the deadliest cancer, often diagnosed at advanced stages. Screening reduces mortality in high-risk individuals. E...

Jul 8 2026 42419775
Utility of E-Nose in Paediatric Respiratory Diseases Using Machine Learning Approach: A Pilot Study.

To assess the feasibility of an electronic nose (e-nose) for volatile organic compounds (VOCs) to classify respiratory diseases and establish a protoc...

Jul 7 2026 42411739
Bioactive environments to combat antimicrobial resistance: artificial intelligence and model-driven microbial biocontrol for living materials.

Antimicrobial resistance (AMR) continues to outpace development of new therapeutics. Many interventions focus on treating infection after it occurs, b...

Jul 7 2026 42411838
Evaluation of a sleep sound analysis smartphone app for home obstructive sleep apnea screening among community-dwelling Chinese adults with hypertension.

PURPOSE: This study aimed to evaluate the validity and feasibility of home obstructive sleep apnea screening using a sleep sound analysis smartphone a...

Jul 7 2026 42412159
Targeting the Gut-Heart Axis in Atherosclerosis: Microbial Metabolites, Molecular Mechanisms, and Precision Therapeutics.

Despite advances in lipid-lowering and anti-inflammatory medications, atherosclerotic cardiovascular disease (ASCVD) continues to be the leading cause...

Jul 7 2026 42412324
Association of C-reactive protein to albumin ratio with progression of CKD and all-cause mortality in diabetic CKD.

INTRODUCTION: The C-reactive protein to albumin ratio (CAR), an integrative biomarker of inflammation and malnutrition, has shown prognostic value in ...

Jul 7 2026 42412363
Smart Speaker-Based Applications to Support Social Connectedness in Older Adult Residents in Affordable Housing: User-Centered Design Study.

BACKGROUND: Older adults in affordable housing face heightened risks of social isolation and loneliness due to limited social networks, transportation...

Jul 7 2026 42412625
Using Machine Learning for Identification of Athlete Availability Predictors in a Multisport Elite Female Athlete Cohort.

Moore, SR, Cantú, EI, Brantner, CL, Britton, ME, DelBiondo, GM, Blue, MNM, Bruinvels, G, Hackney, AC, Register-Mihalik, JK, and Smith-Ryan, AE. Using ...

Jul 7 2026 42413555
A FUCA based MCDM model with complex q rung orthopair fuzzy information for evaluating physical education programs.

The assessment of physical education programs is associated with various contradictory standards, ambiguity, and subjective judgment of the experts, a...

Jul 7 2026 42414356
Heterogeneity, longitudinal decline, and metabolic risk in MRI-based quantification of 20 individual hip and thigh muscles.

Quantifying muscle health at scale has been limited by the difficulty of segmenting individual muscles on MRI. We developed an automated 3D deep-learn...

Jul 7 2026 42414402
A comparative and interpretable machine learning framework for reliable diabetes risk prediction.

Diabetes mellitus is a common type of metabolic illness that is very common worldwide, and in most cases, it results in serious effects like heart dis...

Jul 7 2026 42414449
An Interpretable AI System for Oral Leukoplakia Progression: From Early Screening to Lesion Delineation.

Oral potentially malignant disorders (OPMDs), particularly leukoplakia, represent critical precursors to oral cancer requiring systematic monitoring. ...

Jul 7 2026 42414555
3D OCT-Based Retinal Biomarker Analysis for Automatic Regional-Wise Characterization of Neurodegenerative Diseases.

Neurodegenerative diseases (NDDs) such as Alzheimer's disease (AD), essential tremor (ET), multiple sclerosis (MS), and Parkinson's disease (PD) are c...

Jul 7 2026 42414714
Heatstroke Over the Past Decade: Risk Factors, Long-Term Health Consequences, and Preventive Measures.

BACKGROUND: Heatstroke (HS) encompasses acute multi-organ dysfunction and increases susceptibility to subsequent heat-related conditions, making timel...

Jul 7 2026 42414802
Current Landscape and Future Perspectives of Diabetic Retinopathy Therapy: Pharmacological Targets, Precision Laser Technology, and Clinical Evidence.

Diabetic retinopathy (DR), a major cause of blindness worldwide, poses a substantial and escalating burden on public health. The limitations of curren...

Jul 7 2026 42415853
Hearing Loss in Older Adults: Consistent Determinants Across Two Community-Based Cohorts in Southern China.

BACKGROUND: Hearing loss (HL) is common in older adults and is associated with substantial functional decline, yet community-based evidence on its det...

Jul 7 2026 42416284
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