Rheumatoid Arthritis

Bioactivity of semisynthetic eugenol derivatives against (Lepidoptera: Noctuidae) larvae infesting maize in Colombia.

The anti-acetylcholinesterase, larvicidal, antifeedant activities and general toxicity of 15 semisynthetic eugenol derivatives based on clove oil (including the own oil), were evaluated against the maize armyworm, (J.E. Smith). Therefore, promising eugenol molecules were classified with larvicidal, anti-acetylcholinesterase and antifeedant activities for controlling this pest. During structure-ac...

Therapeutic Enoxaparin in the Morbidly Obese Patient: A Case Report and Review of the Literature.

Enoxaparin is a low molecular weight heparin commonly used in the treatment of venous thromboembolisms (VTEs); however, evidence on optimal empiric dosing recommendations are lacking in patients with morbid obesity. Utilization of an absolute dose cap, anti-Xa monitoring, and reduced empiric dosing are among the techniques used in this population. We describe a case of a morbidly obese man (body-m...

anti-inflammatory and antimicrobial potential of leaf extract from (Clarke) Pamp.

In the present investigation, the bioactive compounds from the leaf extract of showed potent anti-inflammatory and antimicrobial activity. The leaf e...

Development of a competitive enzyme-linked immunosorbent assay for therapeutic drug monitoring of afatinib.

Afatinib is an oral tyrosine kinase inhibitor (TKI) approved for treating advanced non-small cell lung cancer. It is necessary to develop a simple qua...

Anti-microbial Activity of Aqueous Gall Extract against Pathogenic .

BACKGROUND: gall extract is known to have broad spectrum anti-microbial activity . This study was conducted to determine the anti-microbial activity ...

The involvement of phenolic-rich extracts from Galician autochthonous extra-virgin olive oils against the α-glucosidase and α-amylase inhibition.

'Brava' and 'Mansa de Figueiredo' extra-virgin olive oils (EVOOs) are two varieties identified from north-western Spain. A systematic phenolic charact...

Identification of lead anti-human cytomegalovirus compounds targeting MAP4K4 via machine learning analysis of kinase inhibitor screening data.

Chemogenomic approaches involving highly annotated compound sets and cell based high throughput screening are emerging as a means to identify novel dr...

PLGA Microspheres Loaded with β-Cyclodextrin Complexes of Epigallocatechin-3-Gallate for the Anti-Inflammatory Properties in Activated Microglial Cells.

Although epigallocatechin-3-gallate (EG) is well-known as a potent antioxidant and free radical scavenger for neurodegenerative diseases, it still has...

In vitro Anti-cholinesterase and Anti-oxidant Activity of Three Standardised Polyherbal Products Used for Memory Enhancing in Ethnomedicine of South-East Nigeria.

BACKGROUND: Polyherbal standardised extracts used in ethnomedicine of Eastern Nigeria for memory improvements were evaluated for anti-cholinesterases ...

Anti-synchronization of complex-valued memristor-based delayed neural networks.

This paper investigates the anti-synchronization of complex-valued memristor-based neural networks with time delays via designed external controllers....

Pharmacological therapy selection of type 2 diabetes based on the SWARA and modified MULTIMOORA methods under a fuzzy environment.

Medication selection for Type 2 Diabetes (T2D) is a challenging medical decision-making problem involving multiple medications that can be prescribed ...

Structure-function properties of hypolipidemic peptides.

This review addresses the structure-function properties of hypolipidemic peptides. The cholesterol-lowering peptide (lactostatin: IIAEK) operates via ...

A novel triterpenoid 16-hydroxy betulinic acid isolated from attributes multi-faced pharmacological activities.

The aerial parts of extensively used ethnomedicinal plant (Burm. f.) Robinson growing wild in Bangladesh were investigated to isolate and characteriz...

Predicting Visual Acuity by Using Machine Learning in Patients Treated for Neovascular Age-Related Macular Degeneration.

PURPOSE: To predict, by using machine learning, visual acuity (VA) at 3 and 12 months in patients with neovascular age-related macular degeneration (A...

Lipid Metabolism in Patients with Anti-N-Methyl-D-Aspartate Receptor Encephalitis.

OBJECTIVE: Lipid metabolism has been implicated in autoimmune disorders, but its relationship with anti-N-methyl-D-aspartate receptor (anti-NMDAR) enc...

anti-inflammatory and skin protective properties of Virgin coconut oil.

Virgin coconut oil (VCO) has been traditionally used as moisturizer since centuries by people in the tropical region. Clinical studies have revealed t...

A method of gene expression data transfer from cell lines to cancer patients for machine-learning prediction of drug efficiency.

Personalized medicine implies that distinct treatment methods are prescribed to individual patients according several features that may be obtained fr...

Anti-Obesity Property of Lichen Extract in 3T3-L1 Cells and Diet-Induced Obese Mice.

(TV) is an edible lichen that is prevalent in the alpine zone of East Asia. This study evaluated the feasibility of using TV acetone extracts as a fu...

Analysis of Antioxidant and Anti-Inflammatory Activities of Solvent Fractions from Cultivated with Mycelium.

In this study, the crude ethanol cultivated with mycelium (RNGM) extract was solvent fractionated with organic solvents such as -hexane, chloroform,...

Simvastatin and nanofibrous poly(l-lactic acid) scaffolds to promote the odontogenic potential of dental pulp cells in an inflammatory environment.

UNLABELLED: In this study, we investigated the anti-inflammatory, odontogenic and pro-angiogenic effects of integrating simvastatin and nanofibrous po...