Schizophrenia

Risperidone Reduces Matrix Metalloproteinase-9 and Increases Neurotrophin-3 in Schizophrenia Spectrum of Disorder.

Even though earlier studies have reported alteration in the markers of synaptic plasticity (Matrix metalloproteinase-9 [MMP-9] and Neurotrophin-3 [NT-3]), there are no reports about the effect of risperidone on the same. The present study was designed to assess the effect of risperidone on NT-3 and MMP-9 levels in patients with schizophrenia spectrum of disorder and to investigate whether these ma...

Deep HDR Hallucination for Inverse Tone Mapping.

Inverse Tone Mapping (ITM) methods attempt to reconstruct High Dynamic Range (HDR) information from Low Dynamic Range (LDR) image content. The dynamic range of well-exposed areas must be expanded and any missing information due to over/under-exposure must be recovered (hallucinated). The majority of methods focus on the former and are relatively successful, while most attempts on the latter are no...

Going deep into schizophrenia with artificial intelligence.

Despite years of research, the mechanisms governing the onset, relapse, symptomatology, and treatment of schizophrenia (SZ) remain elusive. The lack o...

Schizophrenia: A Survey of Artificial Intelligence Techniques Applied to Detection and Classification.

Artificial Intelligence in healthcare employs machine learning algorithms to emulate human cognition in the analysis of complicated or large sets of d...

Identification of voxel-based texture abnormalities as new biomarkers for schizophrenia and major depressive patients using layer-wise relevance propagation on deep learning decisions.

Non-segmented MRI brain images are used for the identification of new Magnetic Resonance Imaging (MRI) biomarkers able to differentiate between schizo...

EEG microstate features for schizophrenia classification.

Electroencephalography (EEG) microstate analysis is a method wherein spontaneous EEG activity is segmented at sub-second levels to analyze quasi-stabl...

Prediction of functional outcomes of schizophrenia with genetic biomarkers using a bagging ensemble machine learning method with feature selection.

Genetic variants such as single nucleotide polymorphisms (SNPs) have been suggested as potential molecular biomarkers to predict the functional outcom...

Application of machine learning to predict reduction in total PANSS score and enrich enrollment in schizophrenia clinical trials.

Clinical trial efficiency, defined as facilitating patient enrollment, and reducing the time to reach safety and efficacy decision points, is a critic...

The Translational Machine: A novel machine-learning approach to illuminate complex genetic architectures.

The Translational Machine (TM) is a machine learning (ML)-based analytic pipeline that translates genotypic/variant call data into biologically contex...

Features Guided Face Super-Resolution via Hybrid Model of Deep Learning and Random Forests.

Face hallucination or super-resolution is a practical application of general image super-resolution which has been recently studied by many researcher...

FragNet, a Contrastive Learning-Based Transformer Model for Clustering, Interpreting, Visualizing, and Navigating Chemical Space.

The question of molecular similarity is core in cheminformatics and is usually assessed via a comparison based on vectors of properties or molecular ...

Applying a bagging ensemble machine learning approach to predict functional outcome of schizophrenia with clinical symptoms and cognitive functions.

It has been suggested that the relationship between cognitive function and functional outcome in schizophrenia is mediated by clinical symptoms, while...

Machine Learning Reduced Gene/Non-Coding RNA Features That Classify Schizophrenia Patients Accurately and Highlight Insightful Gene Clusters.

RNA-seq has been a powerful method to detect the differentially expressed genes/long non-coding RNAs (lncRNAs) in schizophrenia (SCZ) patients; howeve...

A novel method for clinical risk prediction with low-quality data.

In real-world data, predictive models for clinical risks (such as adverse drug reactions, hospital readmission, and chronic disease onset) are constan...

Sparse deep neural networks on imaging genetics for schizophrenia case-control classification.

Deep learning methods hold strong promise for identifying biomarkers for clinical application. However, current approaches for psychiatric classificat...

HOPES: An Integrative Digital Phenotyping Platform for Data Collection, Monitoring, and Machine Learning.

The collection of data from a personal digital device to characterize current health conditions and behaviors that determine how an individual's healt...

Deep learning based automatic diagnosis of first-episode psychosis, bipolar disorder and healthy controls.

Neuroimaging data driven machine learning based predictive modeling and pattern recognition has been attracted strongly attention in biomedical scienc...

Deep learning applications for the classification of psychiatric disorders using neuroimaging data: Systematic review and meta-analysis.

Deep learning (DL) methods have been increasingly applied to neuroimaging data to identify patients with psychiatric and neurological disorders. This ...

Pattern classification as decision support tool in antipsychotic treatment algorithms.

Pattern classification aims to establish a new approach in personalized treatment. The scope is to tailor treatment on individual characteristics duri...

Face Hallucination With Finishing Touches.

Obtaining a high-quality frontal face image from a low-resolution (LR) non-frontal face image is primarily important for many facial analysis applicat...