Transplantation

Regeneration of Denervated Skeletal Muscles - Brunelli's CNS-PNS Paradigm.

The restoration of voluntary muscle activity in posttraumatic paraplegia in both animal experiments and other clinical applications requires reproducibility of a technically-demanding microsurgical procedure, limited by physicians' understanding of Brunelli's spinal cord grafting paradigm. The insufficient clinical investigation of the long-term benefits of the CNS-PNS graft application warrants a...

Evaluation of Cyclosporine Pharmacokinetic, Monitoring, and Dosing Parameters for GVHD Prophylaxis in Hematopoietic Stem Cell Transplant (HSCT) Recipients.

Allogeneic hematopoietic stem cell transplantation (AHSCT) is a major method of treatment for different hematologic and congenital disease. Graft versus host disease (GvHD) is a life-threatening adverse effect of AHSCT. Cyclosporine is the most important and common agent for GvHD prophylaxis. Because of variable and unpredictable pharmacokinetics of cyclosporine that produces different responses i...

Automatic Organ Segmentation for CT Scans Based on Super-Pixel and Convolutional Neural Networks.

Accurate segmentation of specific organ from computed tomography (CT) scans is a basic and crucial task for accurate diagnosis and treatment. To avoid...

[Neurological contact.].

To what extent is current clinical practice capable of gathering relevant patient data, observing them and giving them adequate information back? To w...

Treatment of Chylothorax with Pleurodesis (A Lesser Known Complication of Behçet's Disease): A Case Report.

Behçet's Disease (BD) is a multisystemic vasculitis which usually affects optical, genital, and oral mucosae and often reoccurs intermittently. Chylot...

Estimating Normal Values of Rare T-Lymphocyte Populations in Peripheral Blood of Healthy Cuban Adults.

INTRODUCTION Flow cytometry allows immunophenotypic characterization of important lymphocyte subpopulations for diagnosis of diseases such as cancer, ...

Multi-Organ Plant Classification Based on Convolutional and Recurrent Neural Networks.

Classification of plants based on a multi-organ approach is very challenging. Although additional data provide more information that might help to dis...

Neural Networks for Prognostication of Patients With Heart Failure.

Background Prognostication of heart failure patients from cardiopulmonary exercise test (CPET) currently involves simplification of complex time-serie...

A hybrid active force control of a lower limb exoskeleton for gait rehabilitation.

Owing to the increasing demand for rehabilitation services, robotics have been engaged in addressing the drawbacks of conventional rehabilitation ther...

COSSMO: predicting competitive alternative splice site selection using deep learning.

MOTIVATION: Alternative splice site selection is inherently competitive and the probability of a given splice site to be used also depends on the stre...

[Comparison of machine learning method and logistic regression model in prediction of acute kidney injury in severely burned patients].

To build risk prediction models for acute kidney injury (AKI) in severely burned patients, and to compare the prediction performance of machine learn...

Pharmacokinetic Therapeutic Drug Monitoring of Advagraf in More Than 500 Adult Renal Transplant Patients, Using an Expert System Online.

BACKGROUND: Immunosuppressant Bayesian dose adjustment (ISBA) is an online expert system, routinely used by approximately 140 transplantation centers ...

Validation of artificial neural networks as a methodology for donor-recipient matching for liver transplantation.

In 2014, we reported a model for donor-recipient (D-R) matching in liver transplantation (LT) based on artificial neural networks (ANNs) from a Spanis...

Artificial neural networks and liver transplantation: Are we ready for self-driving cars?

Integrative Analysis of Proteomics Data to Obtain Clinically Relevant Markers.

The analysis of proteomics data can be significantly challenging. Beyond the technical challenges of accurately identifying and quantifying peptides, ...

XplOit: An Ontology-Based Data Integration Platform Supporting the Development of Predictive Models for Personalized Medicine.

Predictive models can support physicians to tailor interventions and treatments to their individual patients based on their predicted response and ris...

Prevalence of latent Mycobacterium tuberculosis infection in renal transplant recipients.

OBJECTIVE: To estimate the prevalence of latent Mycobacterium tuberculosis infection (LTBI) in renal transplant recipients and to assess sociodemograp...

Outflow Facility in Tube Shunt Fenestration.

AIM: Determination of the effect of varying fenestration technique, and simulated patch graft on outflow facility for Baerveldt tube.

Angioplasty and stenting for the proximal anastomotic stenosis of a brachio-axillary bypass graft using a helical interwoven nitinol stent: A case report.

RATIONALE: Thrombosis due to anastomotic site stenosis is the most common complication in patients with brachio-axillary arteriovenous graft (AVG). In...

Analysis of Interleukin-17 mRNA Level in the Urinary Cells of Kidney Transplant Recipients with Stable Function.

OBJECTIVES: Kidney transplantation supports patients with end-stage kidney diseases. Many factors control the allograft function in kidney transplant ...