Infectious Disease

Vaccines

Latest AI and machine learning research in vaccines for healthcare professionals.

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Conservation region finding for influenza A viruses by machine learning methods of N-linked glycosylation sites and B-cell epitopes.

Influenza type A, a serious infectious disease of the human respiratory tract, poses an enormous thr...

SIMON, an Automated Machine Learning System, Reveals Immune Signatures of Influenza Vaccine Responses.

Machine learning holds considerable promise for understanding complex biological processes such as v...

Sentiment Analysis of Social Media on Childhood Vaccination: Development of an Ontology.

BACKGROUND: Although vaccination rates are above the threshold for herd immunity in South Korea, a g...

IAPSO-AIRS: A novel improved machine learning-based system for wart disease treatment.

Wart disease (WD) is a skin illness on the human body which is caused by the human papillomavirus (H...

Seroprevalence of antibodies for pertussis and diphtheria among people leaving or entering China: a cross-sectional study.

INTRODUCTION: Despite high population immunity, pertussis remains one of the leading causes of vacci...

MHCSeqNet: a deep neural network model for universal MHC binding prediction.

BACKGROUND: Immunotherapy is an emerging approach in cancer treatment that activates the host immune...

Likelihood-Based Methods for Assessing Principal Surrogate Endpoints in Vaccine Trials.

When evaluating principal surrogate biomarkers in vaccine trials, missingness in potential outcomes ...

Quantitative Prediction of the Landscape of T Cell Epitope Immunogenicity in Sequence Space.

Immunodominant T cell epitopes preferentially targeted in multiple individuals are the critical elem...

The use of natural language processing to identify Tdap-related local reactions at five health care systems in the Vaccine Safety Datalink.

OBJECTIVE: Local reactions are the most common vaccine-related adverse event. There is no specific d...

Booster immunity - diagnosis of chronic hepatitis B viral infection.

INTRODUCTION: Diagnosis of chronic hepatitis B virus (HBV) infection particularly its occult form re...

The Immunogenicity of the C Fragment of Tetanus Neurotoxin in Production of Tetanus Antitoxin.

The demand of tetanus antitoxin (TAT) as tetanus treatment in developing and underdeveloped countrie...

Functional expression of porcine interferon-α using a combinational strategy in Pichia pastoris GS115.

Porcine interferon-α (pIFN-α) could be used as the vaccine adjuvant to enhance the antiviral ability...

Leveraging Knowledge Representation to Maintain Immunization Clinical Decision Support.

Immunizations are one of the most cost-effective interventions for preventing morbidity and mortalit...

CbpM and CbpG of Streptococcus Pneumoniae Elicit a High Protection in Mice Challenged with a Serotype 19F Pneumococcus.

Among many pneumococcal antigens, choline-binding proteins (CPBs) display a high immunogenicity in a...

MSIpred: a python package for tumor microsatellite instability classification from tumor mutation annotation data using a support vector machine.

Microsatellite instability (MSI) is characterized by high degree of polymorphism in microsatellite l...

Immunogenicity of Concentrated and Purified Inactivated Avian Influenza Vaccine Formulation.

Avian influenza (AI) H9N2 is a low pathogenic virus subtype belonging to Orthomyxoviridae family. Gi...

Effect of PET-MR Inconsistency in the Kernel Image Reconstruction Method.

Anatomically-driven image reconstruction algorithms have become very popular in positron emission to...

Identification of Immune Signatures of Novel Adjuvant Formulations Using Machine Learning.

Adjuvants have long been critical components of vaccines, but the exact mechanisms of their action a...

Discrimination of "hot potato voice" caused by upper airway obstruction utilizing a support vector machine.

OBJECTIVES/HYPOTHESIS: "Hot potato voice" (HPV) is a thick, muffled voice caused by pharyngeal or la...

Estimation of the Basic Reproduction Number and Vaccination Coverage of Influenza in the United States (2017-18).

BACKGROUND: Determining the epidemic threshold parameter helps health providers calculate the covera...

Updated NACI recommendations for measles post-exposure prophylaxis.

BACKGROUND: Human immune globulin (Ig) products are currently recommended as post-exposure prophylax...

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