Infectious Disease

Vaccines

Latest AI and machine learning research in vaccines for healthcare professionals.

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Optimization on machine learning based approaches for sentiment analysis on HPV vaccines related tweets.

BACKGROUND: Analysing public opinions on HPV vaccines on social media using machine learning based approaches will help us understand the reasons behind the low vaccine coverage and come up with corresponding strategies to improve vaccine uptake.

Mar 3 2017 28253919

Enhancing the Biological Relevance of Machine Learning Classifiers for Reverse Vaccinology.

Reverse vaccinology (RV) is a bioinformatics approach that can predict antigens with protective potential from the protein coding genomes of bacterial pathogens for subunit vaccine design. RV has become firmly established following the development of the BEXSERO® vaccine against Neisseria meningitidis serogroup B. RV studies have begun to incorporate machine learning (ML) techniques to distinguish...

Feb 1 2017 28157153
An expert system for selecting wart treatment method.

As benign tumors, warts are made through the mediation of Human Papillomavirus (HPV) and may grow on all parts of body, especially hands and feet. The...

Jan 6 2017 28086200
Development of an IgY Antibody-Based Immunoassay for the Screening of the CYP2E1 Inhibitor/Enhancer from Herbal Medicines.

Cytochrome P450 (CYP) 2E1 is an important enzyme involved in the metabolism of many endogenous and exogenous compounds. It is essential to evaluate th...

Dec 22 2016 28066249
An inactivated influenza D virus vaccine partially protects cattle from respiratory disease caused by homologous challenge.

Originally isolated from swine, the proposed influenza D virus has since been shown to be common in cattle. Inoculation of IDV to naïve calves resulte...

Dec 21 2016 28110784
Nuclear Magnetic Resonance (NMR) Study for the Detection and Quantitation of Cholesterol in HSV529 Therapeutic Vaccine Candidate.

This study describes the NMR-based method to determine the limit of quantitation (LOQ) and limit of detection (LOD) of cholesterol, a process-related ...

Nov 1 2016 28694932
Emergence of event cascades in inhomogeneous networks.

There is a commonality among contagious diseases, tweets, and neuronal firings that past events facilitate the future occurrence of events. The spread...

Sep 14 2016 27625183
An improved method for predicting interactions between virus and human proteins.

The interaction of virus proteins with host proteins plays a key role in viral infection and consequent pathogenesis. Many computational methods have ...

Jul 10 2016 27397631
A new algorithmic approach for the extraction of temporal associations from clinical narratives with an application to medical product safety surveillance reports.

The sheer volume of textual information that needs to be reviewed and analyzed in many clinical settings requires the automated retrieval of key clini...

Jun 17 2016 27327528
Expression of rabies virus glycoprotein in the methylotrophic yeast Pichia pastoris.

Rabies is a fatal disease that can be prevented by vaccination. Different approaches were investigated to develop novel human rabies vaccines with imp...

Apr 14 2016 28218973
Vaccine and Drug Ontology Studies (VDOS 2014).

The "Vaccine and Drug Ontology Studies" (VDOS) international workshop series focuses on vaccine- and drug-related ontology modeling and applications. ...

Feb 25 2016 26918107
Selenium supplementation has beneficial and detrimental effects on immunity to influenza vaccine in older adults.

BACKGROUND & AIMS: Mortality resulting from influenza (flu) virus infections occurs primarily in the elderly through declining immunity. Studies in mi...

Dec 24 2015 26803169
Reappraisal of the Immunogenicity and Safety of Three Hepatitis A Vaccines in Adolescents.

Although the overall incidence of hepatitis A in Korea has been decreasing, adolescents remain highly vulnerable to its outbreaks. This study was cond...

Dec 24 2015 26770041
Mutagenic Potential ofBos taurus Papillomavirus Type 1 E6 Recombinant Protein: First Description.

Bovine papillomavirus (BPV) is considered a useful model to study HPV oncogenic process. BPV interacts with the host chromatin, resulting in DNA damag...

Dec 9 2015 26783529
Clinical course of H1N1-vaccine-related narcolepsy.

OBJECTIVE: To follow and analyze the clinical course and quality of life of Pandemrix H1N1-vaccine-related narcolepsy (pNT1).

Nov 25 2015 27198942
Persistence of Anti-HBs Among Palestinian Medical Students After 18 - 22 Years of Vaccination: A Cross-Sectional Study.

BACKGROUND: Hepatitis B infection is a global public health problem affecting various sectors in the society. Vaccination is the first line measure to...

Nov 7 2015 26834785
Integrated analysis of oral tongue squamous cell carcinoma identifies key variants and pathways linked to risk habits, HPV, clinical parameters and tumor recurrence.

Oral tongue squamous cell carcinomas (OTSCC) are a homogeneous group of tumors characterized by aggressive behavior, early spread to lymph nodes and a...

Nov 5 2015 26834999
Harnessing Computational Biology for Exact Linear B-Cell Epitope Prediction: A Novel Amino Acid Composition-Based Feature Descriptor.

Proteins embody epitopes that serve as their antigenic determinants. Epitopes occupy a central place in integrative biology, not to mention as targets...

Sep 25 2015 26406767
Can Natural Language Processing Improve the Efficiency of Vaccine Adverse Event Report Review?

BACKGROUND: Individual case review of spontaneous adverse event (AE) reports remains a cornerstone of medical product safety surveillance for industry...

Sep 23 2015 26394725
Synbiotic enhances immune responses against infectious bronchitis, infectious bursal disease, Newcastle disease and avian influenza in broiler chickens.

Increased susceptibility of birds to avian pathogens in intensive husbandry system has emphasized on necessity of improvement of innate and specific i...

Sep 15 2015 26893807
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