AIMC Journal:
BioMed research international
Showing 181 to 190 of 314 articles
PSO-LocBact: A Consensus Method for Optimizing Multiple Classifier Results for Predicting the Subcellular Localization of Bacterial Proteins.
BioMed research international
Nov 19, 2019
Several computational approaches for predicting subcellular localization have been developed and proposed. These approaches provide diverse performance because of their different combinations of protein features, training datasets, training strategie...
Application of Computational Biology and Artificial Intelligence Technologies in Cancer Precision Drug Discovery.
BioMed research international
Nov 11, 2019
Artificial intelligence (AI) proves to have enormous potential in many areas of healthcare including research and chemical discoveries. Using large amounts of aggregated data, the AI can discover and learn further transforming these data into "usable...
A Wrapper Feature Subset Selection Method Based on Randomized Search and Multilayer Structure.
BioMed research international
Nov 4, 2019
The identification of discriminative features from information-rich data with the goal of clinical diagnosis is crucial in the field of biomedical science. In this context, many machine-learning techniques have been widely applied and achieved remark...
Comparison of Bagging and Boosting Ensemble Machine Learning Methods for Automated EMG Signal Classification.
BioMed research international
Oct 31, 2019
The neuromuscular disorders are diagnosed using electromyographic (EMG) signals. Machine learning algorithms are employed as a decision support system to diagnose neuromuscular disorders. This paper compares bagging and boosting ensemble learning met...
Predicting Drug-Disease Associations via Using Gaussian Interaction Profile and Kernel-Based Autoencoder.
BioMed research international
Aug 27, 2019
Computational drug repositioning, designed to identify new indications for existing drugs, significantly reduced the cost and time involved in drug development. Prediction of drug-disease associations is promising for drug repositioning. Recent years...
Analysis of Protein-Protein Functional Associations by Using Gene Ontology and KEGG Pathway.
BioMed research international
Jul 18, 2019
Protein-protein interaction (PPI) plays an extremely remarkable role in the growth, reproduction, and metabolism of all lives. A thorough investigation of PPI can uncover the mechanism of how proteins express their functions. In this study, we used g...
Screening and Bioinformatics Analysis of IgA Nephropathy Gene Based on GEO Databases.
BioMed research international
Jul 16, 2019
PURPOSE: To identify novel biomarkers of IgA nephropathy (IgAN) through bioinformatics analysis and elucidate the possible molecular mechanism.
The Model of Aging Acceleration Network Reveals the Correlation of Alzheimer's Disease and Aging at System Level.
BioMed research international
Jul 14, 2019
As the incidence of senile dementia continues to increase, researches on Alzheimer's disease (AD) have become more and more important. Several studies have reported that there is a close relationship between AD and aging. Some researchers even pointe...
Multivariate Cluster-Based Multifactor Dimensionality Reduction to Identify Genetic Interactions for Multiple Quantitative Phenotypes.
BioMed research international
Jul 11, 2019
To understand the pathophysiology of complex diseases, including hypertension, diabetes, and autism, deleterious phenotypes are unlikely due to the effects of single genes, but rather, gene-gene interactions (GGIs), which are widely analyzed by multi...
Evaluation and Identification of the Neuroprotective Compounds of Xiaoxuming Decoction by Machine Learning: A Novel Mode to Explore the Combination Rules in Traditional Chinese Medicine Prescription.
BioMed research international
Jul 10, 2019
Xiaoxuming decoction (XXMD), a classic traditional Chinese medicine (TCM) prescription, has been used as a therapeutic in the treatment of stroke in clinical practice for over 1200 years. However, the pharmacological mechanisms of XXMD have not yet b...
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