AI Medical Compendium Journal:
Clinica chimica acta; international journal of clinical chemistry

Showing 11 to 20 of 37 articles

Artificial intelligence aided serum protein electrophoresis analysis of Finnish patient samples: Retrospective validation.

Clinica chimica acta; international journal of clinical chemistry
BACKGROUND AND AIMS: Serum protein electrophoresis interpretation requires a substantial amount of manual work. In 2020, Chabrun et al. created a machine learning method called SPECTR for the task. We aimed to validate and test the SPECTR method agai...

MultiThal-classifier, a machine learning-based multi-class model for thalassemia diagnosis and classification.

Clinica chimica acta; international journal of clinical chemistry
BACKGROUND: The differential diagnosis between iron deficiency anemia (IDA) and thalassemia trait (TT) remains a significant clinical challenge. This study aimed to develop a machine learning-based multi-class model to differentiate among Microcytic-...

Screening biomarkers for autism spectrum disorder using plasma proteomics combined with machine learning methods.

Clinica chimica acta; international journal of clinical chemistry
BACKGROUND AND AIMS: Autism spectrum disorder (ASD) is a common neurodevelopmental disorder in children. Early intervention is effective. Investigation of novel blood biomarkers of ASD facilitates early detection and intervention.

A machine learning-based electronic nose for detecting neonatal sepsis: Analysis of volatile organic compound biomarkers in fecal samples.

Clinica chimica acta; international journal of clinical chemistry
BACKGROUND: Neonatal sepsis is a global health threat, contributing to high morbidity and mortality rates among newborns. Recognizing the profound impact of neonatal sepsis on long-term health outcomes emphasizes the critical need for timely detectio...

Development of an equation to predict delta bilirubin levels using machine learning.

Clinica chimica acta; international journal of clinical chemistry
OBJECTIVE: Delta bilirubin (albumin-covalently bound bilirubin) may provide important clinical utility in identifying impaired hepatic excretion of conjugated bilirubin, but it cannot be measured in real-time for diagnostic purposes in clinical labor...

Derivation and external validation of mass spectrometry-based proteomic model using machine learning algorithms to predict plaque rupture in patients with acute coronary syndrome.

Clinica chimica acta; international journal of clinical chemistry
BACKGROUND: A poor prognosis is associated with atherosclerotic plaque rupture (PR) despite after conventional therapy for patients with acute coronary syndrome (ACS). Timely identification of PR improves the risk stratification and prognosis of ACS ...

An artificial intelligence-driven support tool for prediction of urine culture test results.

Clinica chimica acta; international journal of clinical chemistry
BACKGROUND AND AIMS: We aimed to develop an easily deployable artificial intelligence (AI)-driven model for rapid prediction of urine culture test results.

Artificial intelligence in the clinical laboratory.

Clinica chimica acta; international journal of clinical chemistry
Laboratory medicine has become a highly automated medical discipline. Nowadays, artificial intelligence (AI) applied to laboratory medicine is also gaining more and more attention, which can optimize the entire laboratory workflow and even revolution...

A Machine learning model for predicting sepsis based on an optimized assay for microbial cell-free DNA sequencing.

Clinica chimica acta; international journal of clinical chemistry
OBJECTIVE: To integrate an enhanced molecular diagnostic technique to develop and validate a machine-learning model for diagnosing sepsis.

AKIML: An interpretable machine learning model for predicting acute kidney injury within seven days in critically ill patients based on a prospective cohort study.

Clinica chimica acta; international journal of clinical chemistry
BACKGROUND: Early recognition and timely intervention for AKI in critically ill patients were crucial to reduce morbidity and mortality. This study aimed to use biomarkers to construct a optimal machine learning model for early prediction of AKI in c...