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European heart journal. Cardiovascular pharmacotherapy

Showing 1 to 3 of 3 articles

Impact of renal impairment on platelet reactivity and clinical outcomes during chronic dual antiplatelet therapy following coronary stenting.

European heart journal. Cardiovascular pharmacotherapy Dec 17, 2015
AIMS: Clinical utilization of dual antiplatelet therapy (DAPT) in patients with renal impairment (RI) following percutaneous coronary interventions (PCI) represents an urgent, unmet need choosing optimal agents, duration of treatment, and potential d...
Coronary Thrombosis Platelet Aggregation Stents Drug Therapy, Combination Kidney Diseases Prospective Studies Percutaneous Coronary Intervention Female Humans Middle Aged Aged Postoperative Complications Platelet Aggregation Inhibitors Male Blood Platelets Kaplan-Meier Estimate Coronary Disease
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Cenderitide: structural requirements for the creation of a novel dual particulate guanylyl cyclase receptor agonist with renal-enhancing in vivo and ex vivo actions.

European heart journal. Cardiovascular pharmacotherapy Dec 10, 2015
AIMS: Cenderitide is a novel dual natriuretic peptide (NP) receptor chimeric peptide activator, which targets the particulate guanylyl cyclase B (pGC-B) receptor and pGC-A unlike native NPs. Cenderitide was engineered to retain the anti-fibrotic prop...
Snake Venoms Receptors, Atrial Natriuretic Factor Renal Agents Natriuretic Peptides Animals Male Drug Design Glomerular Filtration Rate Humans Dogs HEK293 Cells Kidney Function Tests Cyclic GMP Structure-Activity Relationship Natriuretic Agents Dendroaspis Natriuretic Peptide, C-Type
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New artificial intelligence prediction model using serial prothrombin time international normalized ratio measurements in atrial fibrillation patients on vitamin K antagonists: GARFIELD-AF.

European heart journal. Cardiovascular pharmacotherapy Sep 1, 2020
AIMS: Most clinical risk stratification models are based on measurement at a single time-point rather than serial measurements. Artificial intelligence (AI) is able to predict one-dimensional outcomes from multi-dimensional datasets. Using data from ...
Reproducibility of Results Risk Factors Prospective Studies Female Male Risk Assessment Aged Aged, 80 and over Humans Neural Networks, Computer Databases, Factual Administration, Oral Atrial Fibrillation Registries Stroke Prothrombin Time Drug Therapy, Computer-Assisted Vitamin K Hemorrhage Anticoagulants Blood Coagulation International Normalized Ratio Drug Monitoring Treatment Outcome Time Factors Predictive Value of Tests
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