AIMC Journal:
International journal of molecular sciences

Showing 201 to 210 of 423 articles

Genetic Risk Assessment of Nonsyndromic Cleft Lip with or without Cleft Palate by Linking Genetic Networks and Deep Learning Models.

International journal of molecular sciences Feb 25, 2023
Recent deep learning algorithms have further improved risk classification capabilities. However, an appropriate feature selection method is required to overcome dimensionality issues in population-based genetic studies. In this Korean case-control st...
Cleft Palate Interferon Regulatory Factors Genetic Predisposition to Disease Polymorphism, Single Nucleotide Genotype Cleft Lip Deep Learning Gene Regulatory Networks Risk Assessment Case-Control Studies Humans Risk Factors
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MSEDDI: Multi-Scale Embedding for Predicting Drug-Drug Interaction Events.

International journal of molecular sciences Feb 24, 2023
A norm in modern medicine is to prescribe polypharmacy to treat disease. The core concern with the co-administration of drugs is that it may produce adverse drug-drug interaction (DDI), which can cause unexpected bodily injury. Therefore, it is essen...
Humans Drug Interactions Knowledge Bases Polypharmacy
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Artificial Intelligence-Assisted Meta-Analysis of the Frequency of ACE I/D Polymorphisms in Centenarians and Other Long-Lived Individuals.

International journal of molecular sciences Feb 8, 2023
Current research on the angiotensin-converting-enzyme () gene has yielded controversial results on whether different polymorphisms are linked with human longevity. polymorphisms are a risk factor for Alzheimer's disease and age-onset diseases that ...
Humans Artificial Intelligence Aged, 80 and over Peptidyl-Dipeptidase A Genotype Centenarians Polymorphism, Genetic
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Molecular MRI-Based Monitoring of Cancer Immunotherapy Treatment Response.

International journal of molecular sciences Feb 5, 2023
Immunotherapy constitutes a paradigm shift in cancer treatment. Its FDA approval for several indications has yielded improved prognosis for cases where traditional therapy has shown limited efficiency. However, many patients still fail to benefit fro...
Molecular Imaging Humans Artificial Intelligence Neoplasms Immunotherapy Magnetic Resonance Imaging
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Precision Medicine in Glaucoma: Artificial Intelligence, Biomarkers, Genetics and Redox State.

International journal of molecular sciences Feb 1, 2023
Glaucoma is a multifactorial neurodegenerative illness requiring early diagnosis and strict monitoring of the disease progression. Current exams for diagnosis and prognosis are based on clinical examination, intraocular pressure (IOP) measurements, v...
Glaucoma Artificial Intelligence Humans Intraocular Pressure Oxidation-Reduction Tomography, Optical Coherence Biomarkers Precision Medicine
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Annotation-Free Deep Learning-Based Prediction of Thyroid Molecular Cancer Biomarker BRAF (V600E) from Cytological Slides.

International journal of molecular sciences Jan 28, 2023
Thyroid cancer is the most common endocrine cancer. Papillary thyroid cancer (PTC) is the most prevalent form of malignancy among all thyroid cancers arising from follicular cells. Fine needle aspiration cytology (FNAC) is a non-invasive method regar...
Thyroid Cancer, Papillary Proto-Oncogene Proteins B-raf DNA Mutational Analysis Humans Biomarkers, Tumor Carcinoma, Papillary Thyroid Neoplasms Deep Learning Precision Medicine Mutation
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DeepTP: A Deep Learning Model for Thermophilic Protein Prediction.

International journal of molecular sciences Jan 22, 2023
Thermophilic proteins have important value in the fields of biopharmaceuticals and enzyme engineering. Most existing thermophilic protein prediction models are based on traditional machine learning algorithms and do not fully utilize protein sequence...
Neural Networks, Computer Proteins Machine Learning Algorithms Deep Learning
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Current Role of Delta Radiomics in Head and Neck Oncology.

International journal of molecular sciences Jan 22, 2023
The latest developments in the management of head and neck cancer show an increasing trend in the implementation of novel approaches using artificial intelligence for better patient stratification and treatment-related risk evaluation. Radiomics, or ...
Humans Precision Medicine Artificial Intelligence Head and Neck Neoplasms
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Artificial Intelligence and Machine Learning Technology Driven Modern Drug Discovery and Development.

International journal of molecular sciences Jan 19, 2023
The discovery and advances of medicines may be considered as the ultimate relevant translational science effort that adds to human invulnerability and happiness. But advancing a fresh medication is a quite convoluted, costly, and protracted operation...
Artificial Intelligence Machine Learning Technology Drug Design Humans Neural Networks, Computer Drug Discovery
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Prediction of Bone Healing around Dental Implants in Various Boundary Conditions by Deep Learning Network.

International journal of molecular sciences Jan 18, 2023
Tissue differentiation varies based on patients' conditions, such as occlusal force and bone properties. Thus, the design of the implants needs to take these conditions into account to improve osseointegration. However, the efficiency of the design p...
Bone and Bones Finite Element Analysis Osseointegration Deep Learning Algorithms Dental Implants
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