AI Medical Compendium Journal:
Journal of advanced research

Showing 11 to 20 of 22 articles

SCORCH: Improving structure-based virtual screening with machine learning classifiers, data augmentation, and uncertainty estimation.

Journal of advanced research
INTRODUCTION: The discovery of a new drug is a costly and lengthy endeavour. The computational prediction of which small molecules can bind to a protein target can accelerate this process if the predictions are fast and accurate enough. Recent machin...

The applications of deep learning algorithms on in silico druggable proteins identification.

Journal of advanced research
INTRODUCTION: The top priority in drug development is to identify novel and effective drug targets. In vitro assays are frequently used for this purpose; however, traditional experimental approaches are insufficient for large-scale exploration of nov...

Demystifying the long noncoding RNA landscape of small EVs derived from human mesenchymal stromal cells.

Journal of advanced research
INTRODUCTION: The regenerative capacity of mesenchymal stromal cells or medicinal signaling cells (MSCs) is largely mediated by their secreted small extracellular vesicles (sEVs), and the therapeutic efficacy of sEVs can be enhanced by licensing appr...

Rapid and sensitive UHPLC-MS/MS methods for dietary sample analysis of 43 mycotoxins in China total diet study.

Journal of advanced research
INTRODUCTION: Mycotoxins are toxic metabolites produced by fungi that commonly contaminate foods. As recommended by the World Health Organization, total diet study (TDS) is the most efficient and effective way to estimate the dietary intakes of certa...

NDDRF: A risk factor knowledgebase for personalized prevention of neurodegenerative diseases.

Journal of advanced research
INTRODUCTION: Neurodegenerative diseases (NDDs) are a series of chronic diseases, which are associated with progressive loss of neuronal structure or function. The complex etiologies of the NDDs remain unclear, thus the prevention and early diagnosis...

Dynamics of fractional order nonlinear system: A realistic perception with neutrosophic fuzzy number and Allee effect.

Journal of advanced research
INTRODUCTION: The fusion of fractional order differential equations and fuzzy numbers has been widely used in modelling different engineering and applied sciences problems. In addition to these, the Allee effect, which is of high importance in field ...

A risk prediction model of gene signatures in ovarian cancer through bagging of GA-XGBoost models.

Journal of advanced research
INTRODUCTION: Ovarian cancer (OC) is one of the most frequent gynecologic cancers among women, and high-accuracy risk prediction techniques are essential to effectively select the best intervention strategies and clinical management for OC patients a...

Piperidine based 1,2,3-triazolylacetamide derivatives induce cell cycle arrest and apoptotic cell death in .

Journal of advanced research
The fungal pathogen , is a serious threat to public health and is associated with bloodstream infections causing high mortality particularly in patients with serious medical problems. As this pathogen is generally resistant to all the available clas...

berry related yeast volatiles modify behaviour of flies.

Journal of advanced research
Olfactory cues have a large impact on insect behaviour and fitness consequently showing potential in pest management. Yeast released volatiles are used by insects as olfactory cues for finding feeding and oviposition sites. The yeast strain SB-16-15 ...

Synthesis and characterization of ZnO phytonanocomposite using L. (Loganiaceae) and antimicrobial activity against multidrug-resistant bacterial strains from diabetic foot ulcer.

Journal of advanced research
Nanobiotechnology has been emerged as an efficient technology for the development of antimicrobial nanoparticles through an eco-friendly approach. In this study, green synthesized phytonanocomposite of ZnO from leaf aqueous extract was characterized...