Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Oct 5, 2022
To achieve minimum DNA input requirements for next-generation sequencing (NGS), pathologists visually estimate macrodissection and slide count decisions. Unfortunately, misestimation may cause tissue waste and increased laboratory costs. We developed...
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Sep 10, 2022
Artificial intelligence (AI) solutions that automatically extract information from digital histology images have shown great promise for improving pathological diagnosis. Prior to routine use, it is important to evaluate their predictive performance ...
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Sep 5, 2022
Ovarian carcinoma has the highest mortality of all female reproductive cancers and current treatment has become histotype-specific. Pathologists diagnose five common histotypes by microscopic examination, however, histotype determination is not strai...
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Sep 3, 2022
Anaplastic lymphoma kinase (ALK) and ROS oncogene 1 (ROS1) gene fusions are well-established key players in non-small cell lung cancer (NSCLC). Although their frequency is relatively low, their detection is important for patient care and guides thera...
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Aug 4, 2022
Recent progress in the development of artificial intelligence (AI) has sparked enthusiasm for its potential use in pathology. As pathology labs are currently starting to shift their focus towards AI implementation, a better understanding how AI tools...
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Apr 29, 2022
Accurate diagnosis and grading of needle biopsies are crucial for prostate cancer management. A uropathologist-level artificial intelligence (AI) system could help make unbiased decisions and improve pathologists' efficiency. We previously reported a...
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Apr 8, 2022
Previous studies on deep learning (DL) applications in pathology have focused on pathologist-versus-algorithm comparisons. However, DL will not replace the breadth and contextual knowledge of pathologists; rather, only through their combination may t...
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Feb 23, 2022
Interstitial pneumonia is a heterogeneous disease with a progressive course and poor prognosis, at times even worse than those in the main cancer types. Histopathological examination is crucial for its diagnosis and estimation of prognosis. However, ...
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Oct 5, 2021
Traditional pathology approaches have played an integral role in the delivery of diagnosis, semi-quantitative or qualitative assessment of protein expression, and classification of disease. Technological advances and the increased focus on precision ...
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Jun 24, 2021
Digital pathology provides a possibility for computational analysis of histological slides and automatization of routine pathological tasks. Histological slides are very heterogeneous concerning staining, sections' thickness, and artifacts arising du...