AI Medical Compendium Journal:
Natural product research

Showing 1 to 10 of 14 articles

Anti- activity of clerodane diterpenes and their methyl ester derivatives from (Alismataceae).

Natural product research
The effect of the EtOAc extract of leaves against (trypomastigotes) was evaluated . As this extract caused 100% parasite reduction (at 300 µg/mL), it was subjected to chromatographic fractionation to obtain two related diterpenes, clerodermic () an...

biocontrol of phytopathogenic bacteria using floral essential oils and their synergistic blends.

Natural product research
Chemical compositions of essential oils (EOs) from (EO-PG), (EO-LA) and (EO-CO) flowers were determined by GC-MS and GC-FID. Antibacterial activities were determined by the microdilution broth method in 96-well culture plates and MIC and MBC value...

Design and synthesis of amide derivatives inspired by capsaicin as potential antibacterial and antitumor agents.

Natural product research
Nine amide derivatives inspired by capsaicin (ADICs) were synthesised and evaluated for antibacterial and antitumor activities by a series of standard methods in this study. The results showed that ADICs had good antibacterial and antitumor activity....

Fusaroxazin, a novel cytotoxic and antimicrobial xanthone derivative from .

Natural product research
Oxazines and their derivatives are an uncommon natural heterocyclic compounds, which contain oxygen and nitrogen atoms and possess various bioactivities. A novel 1,4-oxazine-xanthone derivative, fusarioxazin () and three known sterols () were separat...

A new diarylhexane and two new diarylpropanols from the roots of .

Natural product research
A new diarylhexane, kneglobularone B () and two new diarylpropanols, kneglobularols A - B () along with seven known compounds () were isolated and characterized from the roots of It is the first time to find arylpropyl quinone () and isoflavone () i...

Talaromydien a and talaroisocoumarin A, new metabolites from the marine-sourced fungus sp. ZZ1616.

Natural product research
New talaromydien A and talaroisocoumarin A (), together with nine known compounds (-), were isolated from a culture of the marine-derived sp. ZZ1616 in potato dextrose broth medium. Structures of the new compounds were elucidated based on their HRE...

Epigallocatechin gallate has antibacterial and antibiofilm activity in methicillin resistant and susceptible of different lineages in non-cytotoxic concentrations.

Natural product research
is an opportunistic agent that can cause a variety of infections, both hospital and community-acquired. Epigallocatechin gallate (EGCG), a flavonoid present in the leaves of , has different biological activities, including antimicrobial potential. H...

Antitubercular metabolites from the marine-derived fungus strain MF029.

Natural product research
During the systematic screening of bioactive compounds from our marine natural product library, crude extract of the marine-derived fungus strain MF029 exhibited moderate bioactivities against , S, methicillin-resistant , and bacillus Calmette-Guér...

Phytochemical analysis and evaluation of the antioxidant and antiproliferative effects of Tucumã oil nanocapsules in breast adenocarcinoma cells (MCF-7).

Natural product research
In this work was to develop an inedited nanocapsule with tucumã oil (). The oil presents of phytosterols (squalene and β-sitosterol), --beta-carotene, acids oleic and palmitic. Antioxidant activity showed a good performance in DPPH and ABTS assays. T...

α-glucosidase inhibitors isolated from L.

Natural product research
The aim of the study was to isolate digestive enzymes inhibitors from through a bioassay-guided fractionation approach. Repeated silica gel and sephadex LH 20 column chromatographies of bioactive fractions afforded stigmasterol, quercetin and avicul...