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Gender-specific sarcopenia screening in hemodialysis: insights from lower limb strength and physiological indicators.
BMC nephrology
May 19, 2025
OBJECTIVE: Maintenance hemodialysis (MHD) patients often suffer from sarcopenia, affecting lower limb muscle strength and increasing the risk of falls and mortality. This study aims to develop an auxiliary screening model for sarcopenia in MHD patien...
Preoperative DBT-based radiomics for predicting axillary lymph node metastasis in breast cancer: a multi-center study.
BMC medical imaging
May 19, 2025
BACKGROUND: In the prognosis of breast cancer, the status of axillary lymph nodes (ALN) is critically important. While traditional axillary lymph node dissection (ALND) provides comprehensive information, it is associated with high risks. Sentinel ly...
Semiautomated segmentation of breast tumor on automatic breast ultrasound image using a large-scale model with customized modules.
Scientific reports
May 19, 2025
To verify the capability of the Segment Anything Model for medical images in 3D (SAM-Med3D), tailored with low-rank adaptation (LoRA) strategies, in segmenting breast tumors in Automated Breast Ultrasound (ABUS) images. This retrospective study colle...
Identification of a panel of volatile organic compounds in urine for early detection of for bladder cancer.
Scientific reports
May 19, 2025
The absence of specific markers makes early detection of bladder cancer (BC) challenging. Recent studies have reported the reliable diagnostic significance of volatile organic compounds (VOCs) in several cancers. This study aimed to investigate wheth...
Development and validation of a nomogram for differentiating immune checkpoint inhibitor-related pneumonitis from pneumonia in patients undergoing immunochemotherapy: a multicenter, real-world, retrospective study.
Frontiers in immunology
May 19, 2025
BACKGROUND: Immune Checkpoint Inhibitor-related Pneumonitis (CIP) exhibits high morbidity and mortality rates in the real world, often coexisting with pneumonia, particularly after immunochemotherapy. We aimed to develop and validate a non-invasive n...
Study on the relationship between vaginal dose and radiation-induced vaginal injury following cervical cancer radiotherapy, and model development.
Frontiers in public health
May 19, 2025
OBJECTIVE: This study investigates the relationship between vaginal radiation dose and radiation-induced vaginal injury in cervical cancer patients, with the aim of developing a risk prediction model to support personalized treatment strategies.
Global burden of vertebral fractures from 1990 to 2021 and projections for the next three decades.
Journal of orthopaedic surgery and research
May 17, 2025
BACKGROUND: Vertebral fractures are linked to significant disability and mortality risks. Yet, existing studies on their global burden are outdated and lack predictive foresight.
Exploring potential methylation markers for ovarian cancer from cervical scraping samples.
Human genomics
May 17, 2025
BACKGROUND: Ovarian cancer has the highest mortality rate among gynecological cancers, making early detection crucial, as the five-year survival rate drops from 92% with early-stage diagnosis compared to 31% with late-stage diagnosis. Current diagnos...
Brain metabolic imaging-based model identifies cognitive stability in prodromal Alzheimer's disease.
Scientific reports
May 17, 2025
The recent approval of anti-amyloid pharmaceuticals for the treatment of Alzheimer's disease (AD) has created a pressing need for the ability to accurately identify optimal candidates for anti-amyloid therapy, specifically those with evidence for inc...
The underlying molecular mechanisms and biomarkers of Hip fracture combined with deep vein thrombosis based on self sequencing bioinformatics analysis.
Journal of orthopaedic surgery and research
May 16, 2025
BACKGROUND: Thrombus formation is a severe complication in orthopedic surgery, significantly increasing mortality in patients with fractures. Therefore, identifying feature genes to determine thrombus presence in fracture surgeries is critical.
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