Despite the broad variety of available microRNA (miRNA) prediction tools, their application to the discovery and annotation of novel miRNA genes in domestic species is still limited. In this study we designed a comprehensive pipeline (eMIRNA) for miR...
Relevance and penetration of machine learning in clinical practice is a recent phenomenon with multiple applications being currently under development. Deep learning-and especially convolutional neural networks (CNNs)-is a subset of machine learning,...
Neural networks : the official journal of the International Neural Network Society
Dec 6, 2019
Stream data processing has lately gained momentum with the arrival of new Big Data scenarios and applications dealing with continuously produced information flows. Unfortunately, traditional machine learning algorithms are not prepared to tackle the ...
Background and Purpose- Volumes of hemorrhage and perihematomal edema (PHE) are well-established biomarkers of primary and secondary injury, respectively, in spontaneous intracerebral hemorrhage. An automated imaging pipeline capable of accurately an...
Progress in molecular biology and translational science
Dec 6, 2019
Formation of G protein-coupled receptors (GPCRs) dimers and higher order oligomers represents a key mechanism in pleiotropic signaling, yet how individual protomers function within oligomers remains poorly understood. For the Class A/rhodopsin subfam...
IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
Dec 6, 2019
To enhance the performance of the brain-actuated robot system, a novel shared controller based on Bayesian approach is proposed for intelligently combining robot automatic control and brain-actuated control, which takes into account the uncertainty o...
Medical & biological engineering & computing
Dec 6, 2019
Acute lymphoblastic leukaemia (ALL), which is due to the malfunctioning in the bone marrow, is common among people all over the world. The haematologist suffers a lot to discriminate the presence of leukaemia in the patients using the blood smears. T...
Computer systems for medical diagnosis based on machine learning are not mere science fiction. Despite undisputed potential benefits, such systems may also raise problems. Two (interconnected) issues are particularly significant from an ethical point...
BMC medical informatics and decision making
Dec 5, 2019
BACKGROUND: Accurately recognizing rare diseases based on symptom description is an important task in patient triage, early risk stratification, and target therapies. However, due to the very nature of rare diseases, the lack of historical data poses...
BMC medical informatics and decision making
Dec 5, 2019
BACKGROUND: Extracting useful information from biomedical literature plays an important role in the development of modern medicine. In natural language processing, there have been rigorous attempts to find meaningful relationships between entities au...
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