AIMC Topic: Algorithms

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Biomechanics of the Healthy and Keratoconic Corneas: A Combination of the Clinical Data, Finite Element Analysis, and Artificial Neural Network.

Current pharmaceutical design
BACKGROUND: Keratoconus is recognized by asymmetrical thinning and bulging of the cornea, resulting in distortion in the surface of the cornea. Keratoconus also alters the biomechanical properties of the cornea, which can be an indicator of the healt...

Supervised Machine Learning Algorithms for Evaluation of Solid Lipid Nanoparticles and Particle Size.

Combinatorial chemistry & high throughput screening
AIMS AND OBJECTIVES: Solid Lipid Nanoparticles (SLNs) are pharmaceutical delivery systems that have advantages such as controlled drug release, long-term stability etc. Particle Size (PS) is one of the important criteria of SLNs. These factors affect...

Intelligently Applying Artificial Intelligence in Chemoinformatics.

Current topics in medicinal chemistry
The intertwining of chemoinformatics with artificial intelligence (AI) has given a tremendous fillip to the field of drug discovery. With the rapid growth of chemical data from high throughput screening and combinatorial synthesis, AI has become an i...

Deep Learning Electronic Cleansing for Single- and Dual-Energy CT Colonography.

Radiographics : a review publication of the Radiological Society of North America, Inc
Electronic cleansing (EC) is used for computational removal of residual feces and fluid tagged with an orally administered contrast agent on CT colonographic images to improve the visibility of polyps during virtual endoscopic "fly-through" reading. ...

Predicting Inhibitors for Multidrug Resistance Associated Protein-2 Transporter by Machine Learning Approach.

Combinatorial chemistry & high throughput screening
BACKGROUND: The efflux transporter multidrug resistance associated protein-2 belongs to ATP-binding cassette superfamily which plays an important role in multidrug resistance and drugdrug interactions. Efflux transporters are considered to be importa...

Intelligent Control for Human-Robot Cooperation in Orthopedics Surgery.

Advances in experimental medicine and biology
Cooperation between surgeon and robot is one of the key technologies that limit the robot to be widely used in orthopedic clinics. In this study, the evolution of human-robot cooperation methods and the control strategies for typical human-robot coop...

Biological Event Trigger Identification with Noise Contrastive Estimation.

IEEE/ACM transactions on computational biology and bioinformatics
Biological Event Extraction is an important task towards the goal of extracting biomedical knowledge from the scientific publications by capturing biomedical entities and their complex relations from the texts. As a crucial step in event extraction, ...

Deep Forest-based Prediction of Protein Subcellular Localization.

Current gene therapy
MOTIVATION: Knowledge of the correct protein subcellular localization is necessary for understanding the function of a protein and revealing the mechanism of many human diseases due to protein subcellular mislocalization, which is required before app...