AI Medical Compendium Topic

Explore the latest research on artificial intelligence and machine learning in medicine.

Multidrug Resistance-Associated Protein 2

Showing 1 to 2 of 2 articles

Clear Filters

Predicting Inhibitors for Multidrug Resistance Associated Protein-2 Transporter by Machine Learning Approach.

Combinatorial chemistry & high throughput screening 30360705
BACKGROUND: The efflux transporter multidrug resistance associated protein-2 belongs to ATP-binding cassette superfamily which plays an important role in multidrug resistance and drugdrug interactions. Efflux transporters are considered to be importa...
Algorithms Databases, Pharmaceutical Drug Discovery Machine Learning Molecular Structure Multidrug Resistance-Associated Protein 2 Multidrug Resistance-Associated Proteins Quantitative Structure-Activity Relationship Support Vector Machine
View on PubMed DOI

Effect of Genetic Polymorphisms on the Pharmacokinetics of Deferasirox in Healthy Chinese Subjects and an Artificial Neural Networks Model for Pharmacokinetic Prediction.

European journal of drug metabolism and pharmacokinetics 32930952
BACKGROUND AND OBJECTIVE: Deferasirox is an oral iron chelator used to reduce iron levels in iron-overloaded patients with transfusion-dependent anemia or non-transfusion-dependent thalassemia. This study investigated the effects of genetic polymorph...
Adolescent Adult Area Under Curve Asian People Cross-Over Studies Cytochrome P-450 CYP1A1 Deferasirox Drug Compounding Female Glucuronosyltransferase Half-Life Healthy Volunteers Humans Iron Chelating Agents Male Middle Aged Multidrug Resistance-Associated Protein 2 Multidrug Resistance-Associated Proteins Neural Networks, Computer Polymorphism, Genetic Polymorphism, Single Nucleotide Predictive Value of Tests Young Adult
View on PubMed DOI
Popular Topics
Recent Journals