. This study aims to design and implement the first deep learning (DL) model to classify subjects in the prodromic states of Alzheimer's disease (AD) based on resting-state electroencephalographic (EEG) signals.. EEG recordings of 17 healthy controls...
BACKGROUND: Functional gene networks (FGNs) capture functional relationships among genes that vary across tissues and cell types. Construction of cell-type-specific FGNs enables the understanding of cell-type-specific functional gene relationships an...
Alzheimer's disease (AD) is the most common form of dementia. Computer-aided diagnosis (CAD) can help in the early detection of associated cognitive impairment. The aim of this work is to improve the automatic detection of dementia in MRI brain data....
INTRODUCTION: It is critical to develop accurate and universally available biomarkers for dementia diseases to appropriately deal with the dementia problems under world-wide rapid increasing of patients with dementia. In this sense, electroencephalog...
Proceedings of the National Academy of Sciences of the United States of America
Jan 3, 2023
The gap between chronological age (CA) and biological brain age, as estimated from magnetic resonance images (MRIs), reflects how individual patterns of neuroanatomic aging deviate from their typical trajectories. MRI-derived brain age (BA) estimates...
Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Jan 2, 2023
Alzheimer's Disease is the most common cause of dementia. Accurate diagnosis and prognosis of this disease are essential to design an appropriate treatment plan, increasing the life expectancy of the patient. Intense research has been conducted on th...
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Dec 27, 2022
Deep learning (DL) on brain magnetic resonance imaging (MRI) data has shown excellent performance in differentiating individuals with Alzheimer's disease (AD). However, the value of DL in detecting progressive structural MRI (sMRI) abnormalities link...
International journal of medical informatics
Dec 21, 2022
BACKGROUND: Cognitive tests and biomarkers are the key information to assess the severity and track the progression of Alzheimer's' disease (AD) and AD-related dementias (AD/ADRD), yet, both are often only documented in clinical narratives of patient...
BACKGROUND: Beta amyloid in the brain, which was originally confirmed by post-mortem examinations, can now be confirmed in living patients using amyloid positron emission tomography (PET) tracers, and the accuracy of diagnosis can be improved by beta...
Journal of chemical information and modeling
Dec 19, 2022
Intrinsically disordered proteins (IDPs) are proteins without a fixed three-dimensional (3D) structure under physiological conditions and are associated with Parkinson's disease, Alzheimer's disease, cancer, cardiovascular disease, amyloidosis, diabe...