Computer methods and programs in biomedicine
Sep 20, 2020
BACKGROUND AND OBJECTIVE: Alzheimer's disease (AD) is the most common type of dementia that can seriously affect a person's ability to perform daily activities. Estimates indicate that AD may rank third as a cause of death for older people, after hea...
BACKGROUND: Alzheimer's Disease (AD) is a degenerative brain disorder that often occurs in people over 65 years old. As advanced AD is difficult to manage, accurate diagnosis of the disorder is critical. Previous studies have revealed effective deep ...
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
Aug 14, 2020
OBJECTIVE: Efficient prediction of the progression of mild cognitive impairment (MCI) to Alzheimer's disease (AD) is important for the early intervention and management of AD. The aim of our study was to develop a longitudinal structural magnetic res...
INTRODUCTION: Alzheimer's disease (AD) is a complex and heterogeneous disease that affects neuronal cells over time and it is prevalent among all neurodegenerative diseases. Next Generation Sequencing (NGS) techniques are widely used for developing h...
Early identification of individuals at risk of developing Alzheimer's disease (AD) dementia is important for developing disease-modifying therapies. In this study, given multimodal AD markers and clinical diagnosis of an individual from one or more t...
Alzheimer's & dementia : the journal of the Alzheimer's Association
Jul 30, 2020
INTRODUCTION: Identifying cognitively normal individuals at high risk for progression to symptomatic Alzheimer's disease (AD) is critical for early intervention.
The Alzheimer's Disease Neuroimaging (ADNI) database is an expansive undertaking by government, academia, and industry to pool resources and data on subjects at various stage of symptomatic severity due to Alzheimer's disease. As expected, magnetic r...
OBJECTIVE: The aim of this research is to identify the stage of Alzheimer's Disease (AD) patients through the use of mobility data and deep learning models. This process facilitates the monitoring of the disease and allows actions to be taken in orde...
Non-rigid cortical registration is an important and challenging task due to the geometric complexity of the human cortex and the high degree of inter-subject variability. A conventional solution is to use a spherical representation of surface propert...
Tau pathology and brain atrophy are the closest correlate of cognitive decline in Alzheimer's disease (AD). Understanding heterogeneity and longitudinal progression of atrophy during the disease course will play a key role in understanding AD pathoge...