Bioinformatics (Oxford, England)
Oct 1, 2024
SUMMARY: The vast generation of genetic data poses a significant challenge in efficiently uncovering valuable knowledge. Introducing GENEVIC, an AI-driven chat framework that tackles this challenge by bridging the gap between genetic data generation ...
Journal of neuropathology and experimental neurology
Sep 1, 2024
Neuropathological diagnosis of Alzheimer disease (AD) relies on semiquantitative analysis of phosphorylated tau-positive neurofibrillary tangles (NFTs) and neuritic plaques (NPs), without consideration of lesion heterogeneity in individual cases. We ...
Cerebral cortex (New York, N.Y. : 1991)
Aug 1, 2024
In recent years, brain imaging genomics has advanced significantly in revealing underlying pathological mechanisms of Alzheimer's disease (AD) and providing early diagnosis. In this paper, we present a framework for diagnosing AD that integrates magn...
Neuropathology and applied neurobiology
Aug 1, 2024
AIMS: Recent advances in artificial intelligence, particularly with large language models like GPT-4Vision (GPT-4V)-a derivative feature of ChatGPT-have expanded the potential for medical image interpretation. This study evaluates the accuracy of GPT...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2024
The importance of early Alzheimer's Disease screening is becoming more apparent, given the fact that there is no way to revert the patient's status after the onset. However, the diagnostic procedure of Alzheimer's Disease involves a comprehensive ana...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2024
In dementia, particularly Alzheimer's Disease (AD), communication challenges are evident, especially in vocabulary and pragmatic aspects. Affected individuals often use vague, non-specific words, and their speech lacks informative nouns and verbs, le...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2024
Generative approaches for cross-modality transformation have recently gained significant attention in neuroimaging. While most previous work has focused on case-control data, the application of generative models to disorder-specific datasets and thei...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2024
With its superior capability in complex data modeling, hypergraph computation is a powerful tool for many applications. In this work, we propose using hypergraph computation for disease prediction. Hypergraphs allow for the representation of higher-o...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2024
Alzheimer's disease (AD) is a neurodegenerative disease with insidious onset and progressive development. AD is a health issue that is attracting attention as the world's populations get older. Although there is currently no effective treatment for t...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2024
Frontotemporal dementia (FTD) is a typical kind of presenile dementia with three main subtypes: behavioral-variant FTD (bvFTD), non-fluent variant primary progressive aphasia (nfvPPA), and semantic variant primary progressive aphasia (svPPA). Our aim...