AIMC Topic: Amyloid beta-Peptides

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Combination of deep learning and 2D CARS figures for identification of amyloid-β plaques.

Optics express Oct 9, 2023
In vivo imaging and accurate identification of amyloid-β (Aβ) plaque are crucial in Alzheimer's disease (AD) research. In this work, we propose to combine the coherent anti-Stokes Raman scattering (CARS) microscopy, a powerful detection technology fo...
Mice Spectrum Analysis, Raman Animals Deep Learning Plaque, Amyloid Nonlinear Optical Microscopy Amyloid beta-Peptides Alzheimer Disease Brain
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MRI-based Deep Learning Assessment of Amyloid, Tau, and Neurodegeneration Biomarker Status across the Alzheimer Disease Spectrum.

Radiology Oct 1, 2023
Background PET can be used for amyloid-tau-neurodegeneration (ATN) classification in Alzheimer disease, but incurs considerable cost and exposure to ionizing radiation. MRI currently has limited use in characterizing ATN status. Deep learning techniq...
Retrospective Studies Female Humans Biomarkers Deep Learning Cognitive Dysfunction Aged Male Alzheimer Disease Positron-Emission Tomography Apolipoproteins E Magnetic Resonance Imaging Amyloid Amyloid beta-Peptides tau Proteins
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Machine Learning for the Prediction of Amyloid Positivity in Amnestic Mild Cognitive Impairment.

Journal of Alzheimer's disease : JAD Jan 1, 2021
BACKGROUND: Amyloid-β (Aβ) evaluation in amnestic mild cognitive impairment (aMCI) patients is important for predicting conversion to Alzheimer's disease. However, Aβ evaluation through Aβ positron emission tomography (PET) is limited due to high cos...
Cerebral Cortex Neuropsychological Tests Apolipoproteins E Mental Recall Positron-Emission Tomography Hippocampus Area Under Curve Amyloid beta-Peptides Female Reproducibility of Results Risk Factors Aged Machine Learning Algorithms Humans Cognitive Dysfunction Aged, 80 and over Middle Aged Magnetic Resonance Imaging Cohort Studies Male Disease Progression Predictive Value of Tests
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Predicting Amyloid-β Levels in Amnestic Mild Cognitive Impairment Using Machine Learning Techniques.

Journal of Alzheimer's disease : JAD Jan 1, 2020
BACKGROUND: Amyloid-β positivity (Aβ+) based on PET imaging is part of the enrollment criteria for many of the clinical trials of Alzheimer's disease (AD), particularly in trials for amyloid-targeted therapy. Predicting Aβ positivity prior to PET ima...
Apolipoprotein E4 Amyloid beta-Peptides Female Gene Frequency Alleles Positron-Emission Tomography Neuropsychological Tests Cognitive Dysfunction Neuroimaging Aged Magnetic Resonance Imaging Male Biomarkers Humans Middle Aged Brain Machine Learning
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