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Matrix Metalloproteinase 2

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The effect of thalidomide on the invasive ability of gastric cancer cells by regulating miR-524-5p/FSTL1.

Cellular and molecular biology (Noisy-le-Grand, France)
This study aimed to investigate the effect of thalidomide (Thal) regulating microRNA (miR)-524-5p/follistatin-like protein 1 (FSTL1) on the invasion ability of gastric cancer cells. For this purpose, real-time fluorescent quantitative PCR (RT-qPCR) w...

Propofol affects the growth and metastasis of pancreatic cancer via ADAM8.

Pharmacological reports : PR
BACKGROUND: Anesthesia is a major component of surgery and recently considered an important regulator of cell phenotypes. Here we aimed to investigate propofol, an anesthesia drug, in suppressing pancreatic cancer (PDAC), focusing on A disintegrin an...

6-Gingerol inhibits hair cycle via induction of MMP2 and MMP9 expression.

Anais da Academia Brasileira de Ciencias
6-Gingerol is the major active constituent of ginger. In the current study, we aimed to investigate the mechanisms underlying the effects of 6-Gingerol on hair growth. Mice were randomly divided into five groups; after hair depilation (day 0), mice w...

Effect of doxycycline on transforming growth factor-beta-1-induced matrix metalloproteinase 2 expression, migration, and collagen contraction in nasal polyp-derived fibroblasts.

American journal of rhinology & allergy
PURPOSE: It is well known that doxycycline has antibacterial and anti-inflammatory effects. In this study, we aimed to investigate the effects of doxycycline on the transforming growth factor (TGF) beta 1-induced matrix metalloproteinase (MMP) 2 expr...

Exposure to fipronil elevates systolic blood pressure and disturbs related biomarkers in plasma of rats.

Environmental toxicology and pharmacology
Recent reports show that fipronil affects non-target organisms, including environmental species populations and potentially humans. We aimed to examine if fipronil exposure affects the systolic blood pressure and related biomarkers. Thus, fipronil wa...

Nanoscale Robots Exhibiting Quorum Sensing.

Artificial life
Multi-agent systems demonstrate the ability to collectively perform complex tasks (e.g., construction, search, and locomotion) with greater speed, efficiency, or effectiveness than could a single agent alone. Direct and indirect coordination methods ...

A disease network-based deep learning approach for characterizing melanoma.

International journal of cancer
Multiple types of genomic variations are present in cutaneous melanoma and some of the genomic features may have an impact on the prognosis of the disease. The access to genomics data via public repositories such as The Cancer Genome Atlas (TCGA) all...