Collagen peptides are ubiquitously applied in food systems for their versatile bioactivities but face constraints from labor-intensive enzymatic screening and zoonotic risks from terrestrial sources. This study developed machine learning (ML) models ...
Survivors of severe COVID-19 often suffer from long-term respiratory issues, but the molecular drivers of this damage remain unclear. This study explored the dynamics of inflammatory, fibrotic, and endothelial biomarkers in hospitalized COVID-19 pati...
Diabetic kidney disease (DKD) is a serious complication of diabetes patients with long time duration, presenting with albuminuria and/or a reduced estimated glomerular filtration rate (eGFR), and without symptoms of other primary causes of kidney inj...
BACKGROUND: Matrix metalloproteinase-2 (MMP-2) secretion homeostasis, governed by the multifaceted interplay of skin stretching, is a pivotal determinant influencing wound healing dynamics. This investigation endeavors to devise an artificial intelli...
Cellular and molecular biology (Noisy-le-Grand, France)
Dec 20, 2023
This study aimed to investigate the effect of thalidomide (Thal) regulating microRNA (miR)-524-5p/follistatin-like protein 1 (FSTL1) on the invasion ability of gastric cancer cells. For this purpose, real-time fluorescent quantitative PCR (RT-qPCR) w...
Multiple types of genomic variations are present in cutaneous melanoma and some of the genomic features may have an impact on the prognosis of the disease. The access to genomics data via public repositories such as The Cancer Genome Atlas (TCGA) all...
BACKGROUND: Anesthesia is a major component of surgery and recently considered an important regulator of cell phenotypes. Here we aimed to investigate propofol, an anesthesia drug, in suppressing pancreatic cancer (PDAC), focusing on A disintegrin an...
Environmental toxicology and pharmacology
Dec 31, 2015
Recent reports show that fipronil affects non-target organisms, including environmental species populations and potentially humans. We aimed to examine if fipronil exposure affects the systolic blood pressure and related biomarkers. Thus, fipronil wa...
BACKGROUND: The coexistence of hepatic fibrosis (HF) and inflammatory bowel disease (IBD) represents a significant clinical concern due to their poorly characterized shared pathogenic mechanisms. Current limitations in identifying common biomarkers f...
Multi-agent systems demonstrate the ability to collectively perform complex tasks (e.g., construction, search, and locomotion) with greater speed, efficiency, or effectiveness than could a single agent alone. Direct and indirect coordination methods ...
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