Deep learning models have advanced our ability to predict cell-type-specific chromatin patterns from transcription factor (TF) binding motifs, but their application to perturbed contexts remains limited. We applied transfer learning to predict how co...
Journal of agricultural and food chemistry
Feb 27, 2025
A large number of mycotoxins and related fungal metabolites have not been assessed in terms of their toxicological impacts. Current methodologies often prioritize specific target families, neglecting the complexity and presence of co-occurring compou...
Bionic flapping wing robots achieve flight by imitating animal flapping wings, which are safe, flexible, and efficient. Their practicality and human-machine symbiosis in narrow and complex environments are better than traditional fixed-wing or multir...
BACKGROUND: Neuropathic pain (NP) can be induced by a variety of clinical conditions, such as spinal cord injury, lumbar disc herniation (LDH), lumbar spinal stenosis, diabetes, herpes zoster, and spinal cord tumors, and inflammatory stimuli. The pat...
Lipids are critical precursors of aroma compounds in beef tallow. This study investigated how enzymatic hydrolysis treatment affected the aroma precursors and flavor of beef tallow during the manufacturing process. Using gas chromatography-mass spect...
Mutation research. Genetic toxicology and environmental mutagenesis
Feb 26, 2025
This study aimed to develop an in silico model for predicting human carcinogenicity using advanced deep learning techniques, specifically Graph Neural Networks (GNN), through a multitask learning (MTL) approach. The MTL framework leveraged auxiliary ...
In eukaryotic cells, DNA replication is organised both spatially and temporally, as evidenced by the stage-specific spatial distribution of replication foci in the nucleus. Despite the genetic association of aberrant DNA replication with numerous hum...
Feline chronic kidney disease (CKD) is one of the most frequently encountered diseases in veterinary practice, and the leading cause of mortality in cats over five years of age. While diagnosing advanced CKD is straightforward, current routine tests ...
Although legged robots have demonstrated effective mobility in some natural settings, as robot size decreases, obstacles in their environment become challenging to overcome. Small arthropods scale obstacles many times their size through jumps powered...
The oviduct is the site of fertilization and preimplantation embryo development in mammals. Evidence suggests that gametes alter oviductal gene expression. To delineate the adaptive interactions between the oviduct and gamete/embryo, we performed a m...
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